KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPX5
All Species:
4.55
Human Site:
S168
Identified Species:
10
UniProt:
O75715
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75715
NP_001500.1
221
25202
S168
E
I
L
G
T
F
K
S
I
S
W
D
P
V
K
Chimpanzee
Pan troglodytes
Q0EFA0
201
21781
L147
A
L
M
T
D
P
K
L
I
T
W
S
P
V
C
Rhesus Macaque
Macaca mulatta
NP_001152774
221
25194
S168
E
I
L
G
T
F
K
S
I
S
W
D
P
V
K
Dog
Lupus familis
XP_545450
154
17353
F116
V
H
D
I
R
W
N
F
E
K
F
L
V
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P21765
221
25363
H168
E
T
V
V
M
S
K
H
T
S
W
E
P
I
K
Rat
Rattus norvegicus
P30710
221
25366
H168
E
T
V
V
T
S
K
H
T
F
W
E
P
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001156704
219
24474
N166
E
E
F
G
N
P
K
N
L
F
W
E
P
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001131027
222
24765
N166
E
S
F
G
A
T
S
N
R
L
F
W
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95003
224
25537
E170
D
K
I
G
K
T
D
E
L
M
Y
N
P
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04922
169
18926
N131
L
I
D
A
I
K
W
N
F
T
K
F
L
V
S
Baker's Yeast
Sacchar. cerevisiae
P38143
162
18388
I124
G
L
L
G
F
K
G
I
K
W
N
F
E
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
98.6
54.7
N.A.
76
75.1
N.A.
N.A.
61.9
N.A.
53.1
N.A.
N.A.
N.A.
36.1
N.A.
Protein Similarity:
100
55.6
99
62.9
N.A.
87.7
87.7
N.A.
N.A.
77.3
N.A.
67.1
N.A.
N.A.
N.A.
53.5
N.A.
P-Site Identity:
100
33.3
100
0
N.A.
40
40
N.A.
N.A.
33.3
N.A.
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
53.3
100
13.3
N.A.
60
60
N.A.
N.A.
66.6
N.A.
26.6
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
19
0
10
0
10
0
0
0
0
19
0
0
0
% D
% Glu:
55
10
0
0
0
0
0
10
10
0
0
28
19
0
0
% E
% Phe:
0
0
19
0
10
19
0
10
10
19
19
19
0
0
10
% F
% Gly:
10
0
0
55
0
0
10
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
28
10
10
10
0
0
10
28
0
0
0
0
19
0
% I
% Lys:
0
10
0
0
10
19
55
0
10
10
10
0
0
10
37
% K
% Leu:
10
19
28
0
0
0
0
10
19
10
0
10
10
10
10
% L
% Met:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
28
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
19
0
0
0
0
0
0
64
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
19
% R
% Ser:
0
10
0
0
0
19
10
19
0
28
0
10
0
0
10
% S
% Thr:
0
19
0
10
28
19
0
0
19
19
0
0
0
0
0
% T
% Val:
10
0
19
19
0
0
0
0
0
0
0
0
10
46
0
% V
% Trp:
0
0
0
0
0
10
10
0
0
10
55
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _