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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPX5 All Species: 13.03
Human Site: S199 Identified Species: 28.67
UniProt: O75715 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75715 NP_001500.1 221 25202 S199 G I P V M R W S H R A T V S S
Chimpanzee Pan troglodytes Q0EFA0 201 21781 S178 G V P L R R Y S R R F Q T I D
Rhesus Macaque Macaca mulatta NP_001152774 221 25194 S199 G I P V M R W S H R A T V S S
Dog Lupus familis XP_545450 154 17353 H133 V P V M R W F H Q A P V S T V
Cat Felis silvestris
Mouse Mus musculus P21765 221 25363 F199 G V P V M R W F H Q A P V S T
Rat Rattus norvegicus P30710 221 25366 F199 G V P V M R W F H Q A P V S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001156704 219 24474 Y197 G V P V M R W Y H R A N I A T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001131027 222 24765 F198 G R P V M R W F P R V N V S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95003 224 25537 R199 R N G Q P R F R F H P T A W S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04922 169 18926 S148 G K V L Q R Y S P R T S P L Q
Baker's Yeast Sacchar. cerevisiae P38143 162 18388 Q141 D S N G K V V Q R F S S L T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.4 98.6 54.7 N.A. 76 75.1 N.A. N.A. 61.9 N.A. 53.1 N.A. N.A. N.A. 36.1 N.A.
Protein Similarity: 100 55.6 99 62.9 N.A. 87.7 87.7 N.A. N.A. 77.3 N.A. 67.1 N.A. N.A. N.A. 53.5 N.A.
P-Site Identity: 100 33.3 100 0 N.A. 66.6 66.6 N.A. N.A. 60 N.A. 60 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 53.3 100 20 N.A. 86.6 86.6 N.A. N.A. 86.6 N.A. 60 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.7 33.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.6 49.7 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 46 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 19 28 10 10 10 0 0 0 0 % F
% Gly: 73 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 46 10 0 0 0 0 0 % H
% Ile: 0 19 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 19 0 0 0 0 0 0 0 0 10 10 0 % L
% Met: 0 0 0 10 55 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 0 0 0 0 19 0 0 0 % N
% Pro: 0 10 64 0 10 0 0 0 19 0 19 19 10 0 0 % P
% Gln: 0 0 0 10 10 0 0 10 10 19 0 10 0 0 10 % Q
% Arg: 10 10 0 0 19 82 0 10 19 55 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 37 0 0 10 19 10 46 28 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 28 10 19 28 % T
% Val: 10 37 19 55 0 10 10 0 0 0 10 10 46 0 10 % V
% Trp: 0 0 0 0 0 10 55 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 19 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _