KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPX5
All Species:
12.12
Human Site:
S22
Identified Species:
26.67
UniProt:
O75715
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75715
NP_001500.1
221
25202
S22
L
A
C
F
V
Q
T
S
P
K
Q
E
K
M
K
Chimpanzee
Pan troglodytes
Q0EFA0
201
21781
A19
Q
S
V
Y
A
F
S
A
R
P
L
A
G
G
E
Rhesus Macaque
Macaca mulatta
NP_001152774
221
25194
S22
L
A
C
F
V
Q
T
S
P
K
Q
E
T
M
K
Dog
Lupus familis
XP_545450
154
17353
Cat
Felis silvestris
Mouse
Mus musculus
P21765
221
25363
T22
L
A
S
Y
V
Q
T
T
P
R
P
E
K
M
K
Rat
Rattus norvegicus
P30710
221
25366
T22
L
A
S
Y
V
Q
T
T
P
R
L
E
K
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001156704
219
24474
G20
L
A
G
L
V
P
L
G
Q
G
Q
E
R
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001131027
222
24765
A22
L
A
L
M
H
K
I
A
A
L
S
N
T
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95003
224
25537
A23
I
I
G
I
S
C
T
A
T
V
D
E
T
M
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04922
169
18926
Baker's Yeast
Sacchar. cerevisiae
P38143
162
18388
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
98.6
54.7
N.A.
76
75.1
N.A.
N.A.
61.9
N.A.
53.1
N.A.
N.A.
N.A.
36.1
N.A.
Protein Similarity:
100
55.6
99
62.9
N.A.
87.7
87.7
N.A.
N.A.
77.3
N.A.
67.1
N.A.
N.A.
N.A.
53.5
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
66.6
66.6
N.A.
N.A.
40
N.A.
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
33.3
93.3
0
N.A.
86.6
86.6
N.A.
N.A.
46.6
N.A.
26.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.6
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
10
0
0
28
10
0
0
10
0
0
10
% A
% Cys:
0
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
55
0
10
10
% E
% Phe:
0
0
0
19
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
0
0
0
0
10
0
10
0
0
10
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
19
0
0
28
0
46
% K
% Leu:
55
0
10
10
0
0
10
0
0
10
19
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
46
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
37
10
10
0
0
0
0
% P
% Gln:
10
0
0
0
0
37
0
0
10
0
28
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
19
0
0
10
0
10
% R
% Ser:
0
10
19
0
10
0
10
19
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
46
19
10
0
0
0
28
0
0
% T
% Val:
0
0
10
0
46
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _