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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPX5 All Species: 18.79
Human Site: Y43 Identified Species: 41.33
UniProt: O75715 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75715 NP_001500.1 221 25202 Y43 E K G T I Y D Y E A I A L N K
Chimpanzee Pan troglodytes Q0EFA0 201 21781 L38 G S L R G K V L L I E N V A S
Rhesus Macaque Macaca mulatta NP_001152774 221 25194 Y43 E K G T I Y D Y E A I A L N K
Dog Lupus familis XP_545450 154 17353 N9 V Q C S Y I G N H C T R E L N
Cat Felis silvestris
Mouse Mus musculus P21765 221 25363 Y43 V K G T I Y D Y E A L S L N G
Rat Rattus norvegicus P30710 221 25366 Y43 V K G T I Y N Y E A L S L N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001156704 219 24474 Y41 V R G T I Y D Y G A L T I D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001131027 222 24765 Y41 A G D S F H N Y G A K T I N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95003 224 25537 D43 N T N Q S I F D F Q I E T L Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04922 169 18926 L24 I G G N D V S L D Q Y K G K T
Baker's Yeast Sacchar. cerevisiae P38143 162 18388 S17 C K D K K G E S F K F D Q L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.4 98.6 54.7 N.A. 76 75.1 N.A. N.A. 61.9 N.A. 53.1 N.A. N.A. N.A. 36.1 N.A.
Protein Similarity: 100 55.6 99 62.9 N.A. 87.7 87.7 N.A. N.A. 77.3 N.A. 67.1 N.A. N.A. N.A. 53.5 N.A.
P-Site Identity: 100 0 100 0 N.A. 73.3 66.6 N.A. N.A. 46.6 N.A. 20 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 6.6 100 13.3 N.A. 86.6 86.6 N.A. N.A. 73.3 N.A. 46.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.7 33.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.6 49.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 55 0 19 0 10 0 % A
% Cys: 10 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 19 0 10 0 37 10 10 0 0 10 0 10 0 % D
% Glu: 19 0 0 0 0 0 10 0 37 0 10 10 10 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 19 0 10 0 0 0 0 % F
% Gly: 10 19 55 0 10 10 10 0 19 0 0 0 10 0 37 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 46 19 0 0 0 10 28 0 19 0 0 % I
% Lys: 0 46 0 10 10 10 0 0 0 10 10 10 0 10 28 % K
% Leu: 0 0 10 0 0 0 0 19 10 0 28 0 37 28 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 10 0 0 19 10 0 0 0 10 0 46 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 10 0 0 0 0 0 19 0 0 10 0 10 % Q
% Arg: 0 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 10 0 19 10 0 10 10 0 0 0 19 0 0 10 % S
% Thr: 0 10 0 46 0 0 0 0 0 0 10 19 10 0 10 % T
% Val: 37 0 0 0 0 10 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 46 0 55 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _