KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A12
All Species:
25.45
Human Site:
S211
Identified Species:
43.08
UniProt:
O75746
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75746
NP_003696.2
678
74762
S211
S
A
A
G
G
S
I
S
H
Q
V
S
F
S
Y
Chimpanzee
Pan troglodytes
XP_001145847
680
74987
S213
S
A
A
G
G
S
I
S
H
Q
V
S
F
S
Y
Rhesus Macaque
Macaca mulatta
XP_001085208
678
74724
S211
S
A
A
G
G
S
I
S
H
Q
V
S
F
S
Y
Dog
Lupus familis
XP_535962
678
74780
S211
S
A
A
G
G
S
I
S
H
Q
V
S
F
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH59
677
74551
S211
S
A
A
G
G
G
T
S
H
Q
V
S
F
S
Y
Rat
Rattus norvegicus
XP_342641
717
78438
S253
A
A
A
G
G
T
R
S
H
Q
V
S
F
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514496
680
74679
A213
S
A
A
G
G
S
I
A
H
Q
V
S
F
S
Y
Chicken
Gallus gallus
XP_428938
642
70679
M196
F
N
A
L
L
N
N
M
D
L
V
R
K
I
Y
Frog
Xenopus laevis
Q7ZY36
473
52338
N34
L
F
H
K
L
D
V
N
K
D
G
K
V
D
I
Zebra Danio
Brachydanio rerio
NP_997947
682
75371
S212
S
A
A
G
G
G
T
S
H
M
V
S
F
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA73
695
76736
G227
N
L
V
S
V
T
E
G
H
K
V
S
F
P
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21153
707
78652
G252
A
V
S
G
G
A
S
G
H
K
V
T
F
P
Y
Sea Urchin
Strong. purpuratus
XP_785145
691
77086
K239
T
V
A
G
G
E
T
K
H
L
V
S
F
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12482
902
104286
K309
L
S
N
T
E
L
L
K
A
D
N
N
S
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.8
97.7
N.A.
96.7
72.5
N.A.
85.5
83.1
20.2
77.5
N.A.
57.1
N.A.
52
60.7
Protein Similarity:
100
99.4
99.8
98.9
N.A.
98.5
81.8
N.A.
89.8
89.3
34.2
86.9
N.A.
73.3
N.A.
68.7
74.1
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
93.3
20
0
80
N.A.
33.3
N.A.
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
100
26.6
13.3
80
N.A.
53.3
N.A.
73.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
58
72
0
0
8
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
15
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
79
0
0
% F
% Gly:
0
0
0
72
72
15
0
15
0
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
79
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
36
0
0
0
0
0
0
15
8
% I
% Lys:
0
0
0
8
0
0
0
15
8
15
0
8
8
0
0
% K
% Leu:
15
8
0
8
15
8
8
0
0
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
8
8
8
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
50
8
8
8
0
36
8
50
0
0
0
72
8
58
0
% S
% Thr:
8
0
0
8
0
15
22
0
0
0
0
8
0
0
0
% T
% Val:
0
15
8
0
8
0
8
0
0
0
86
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _