KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A12
All Species:
21.52
Human Site:
S664
Identified Species:
36.41
UniProt:
O75746
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75746
NP_003696.2
678
74762
S664
L
P
K
F
K
S
P
S
V
A
V
V
Q
P
K
Chimpanzee
Pan troglodytes
XP_001145847
680
74987
S666
L
P
K
F
K
S
P
S
V
A
V
V
Q
P
K
Rhesus Macaque
Macaca mulatta
XP_001085208
678
74724
S664
L
P
K
F
K
S
P
S
V
A
V
V
Q
P
K
Dog
Lupus familis
XP_535962
678
74780
S664
L
P
K
F
K
S
P
S
V
A
V
V
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH59
677
74551
S664
L
P
K
F
K
S
P
S
V
A
V
A
Q
P
K
Rat
Rattus norvegicus
XP_342641
717
78438
Y699
I
E
N
K
F
G
L
Y
L
P
L
F
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514496
680
74679
V666
L
P
K
F
K
S
P
V
V
G
V
V
P
P
K
Chicken
Gallus gallus
XP_428938
642
70679
K627
K
F
G
L
Y
L
P
K
F
R
S
S
G
T
V
Frog
Xenopus laevis
Q7ZY36
473
52338
S460
V
L
P
A
V
S
I
S
Y
V
V
Y
E
K
M
Zebra Danio
Brachydanio rerio
NP_997947
682
75371
G666
L
P
K
F
K
S
S
G
I
S
T
I
H
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA73
695
76736
G681
G
L
Y
L
P
R
F
G
R
G
V
T
A
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21153
707
78652
S690
K
L
A
A
A
T
F
S
G
I
E
H
K
F
G
Sea Urchin
Strong. purpuratus
XP_785145
691
77086
G677
S
G
V
E
T
K
F
G
L
F
L
P
K
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12482
902
104286
I876
C
Q
I
A
K
T
F
I
D
L
D
N
N
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.8
97.7
N.A.
96.7
72.5
N.A.
85.5
83.1
20.2
77.5
N.A.
57.1
N.A.
52
60.7
Protein Similarity:
100
99.4
99.8
98.9
N.A.
98.5
81.8
N.A.
89.8
89.3
34.2
86.9
N.A.
73.3
N.A.
68.7
74.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
80
6.6
20
46.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
80
6.6
33.3
73.3
N.A.
6.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
22
8
0
0
0
0
36
0
8
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
8
0
8
0
8
% E
% Phe:
0
8
0
50
8
0
29
0
8
8
0
8
0
22
0
% F
% Gly:
8
8
8
0
0
8
0
22
8
15
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
8
0
0
0
8
8
8
8
0
8
0
0
0
% I
% Lys:
15
0
50
8
58
8
0
8
0
0
0
0
22
8
43
% K
% Leu:
50
22
0
15
0
8
8
0
15
8
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
50
8
0
8
0
50
0
0
8
0
8
8
50
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
36
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
58
8
50
0
8
8
8
0
8
22
% S
% Thr:
0
0
0
0
8
15
0
0
0
0
8
8
0
8
0
% T
% Val:
8
0
8
0
8
0
0
8
43
8
58
36
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
8
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _