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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A12
All Species:
10.45
Human Site:
T677
Identified Species:
17.69
UniProt:
O75746
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75746
NP_003696.2
678
74762
T677
P
K
A
A
V
A
A
T
Q
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001145847
680
74987
T679
P
K
A
A
V
A
A
T
Q
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001085208
678
74724
T677
P
K
A
A
V
A
A
T
Q
_
_
_
_
_
_
Dog
Lupus familis
XP_535962
678
74780
A677
S
K
A
V
A
A
A
A
Q
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH59
677
74551
Rat
Rattus norvegicus
XP_342641
717
78438
V712
P
S
A
S
T
S
K
V
T
A
V
G
S
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514496
680
74679
Q679
P
K
A
A
A
P
A
Q
S
_
_
_
_
_
_
Chicken
Gallus gallus
XP_428938
642
70679
S640
T
V
S
A
Q
L
K
S
G
S
_
_
_
_
_
Frog
Xenopus laevis
Q7ZY36
473
52338
Zebra Danio
Brachydanio rerio
NP_997947
682
75371
A679
P
E
T
P
K
E
T
A
G
A
S
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA73
695
76736
G694
A
S
P
S
T
A
T
G
S
_
_
_
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21153
707
78652
F703
F
G
L
F
L
P
K
F
E
T
S
K
_
_
_
Sea Urchin
Strong. purpuratus
XP_785145
691
77086
A690
F
R
N
L
Q
P
Q
A
T
_
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12482
902
104286
V889
F
S
R
F
D
S
S
V
Y
K
N
F
Q
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.8
97.7
N.A.
96.7
72.5
N.A.
85.5
83.1
20.2
77.5
N.A.
57.1
N.A.
52
60.7
Protein Similarity:
100
99.4
99.8
98.9
N.A.
98.5
81.8
N.A.
89.8
89.3
34.2
86.9
N.A.
73.3
N.A.
68.7
74.1
P-Site Identity:
100
100
100
55.5
N.A.
0
15.3
N.A.
55.5
10
0
9
N.A.
11.1
N.A.
0
0
P-Site Similarity:
100
100
100
55.5
N.A.
0
38.4
N.A.
55.5
30
0
18.1
N.A.
22.2
N.A.
16.6
11.1
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
43
36
15
36
36
22
0
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
8
0
0
0
0
8
0
% E
% Phe:
22
0
0
15
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
15
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
36
0
0
8
0
22
0
0
8
0
8
0
0
0
% K
% Leu:
0
0
8
8
8
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
43
0
8
8
0
22
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
8
8
29
0
0
0
8
0
0
% Q
% Arg:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
22
8
15
0
15
8
8
15
8
15
0
8
0
0
% S
% Thr:
8
0
8
0
15
0
15
22
15
8
0
0
0
0
0
% T
% Val:
0
8
0
8
22
0
0
15
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
50
58
65
72
79
79
% _