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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A12
All Species:
21.21
Human Site:
Y47
Identified Species:
35.9
UniProt:
O75746
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75746
NP_003696.2
678
74762
Y47
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Chimpanzee
Pan troglodytes
XP_001145847
680
74987
Y49
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Rhesus Macaque
Macaca mulatta
XP_001085208
678
74724
Y47
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Dog
Lupus familis
XP_535962
678
74780
Y47
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH59
677
74551
Y47
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Rat
Rattus norvegicus
XP_342641
717
78438
F89
V
T
R
Y
L
N
I
F
G
E
S
Q
P
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514496
680
74679
V49
E
A
R
V
L
K
R
V
S
A
S
L
G
K
S
Chicken
Gallus gallus
XP_428938
642
70679
E48
F
Q
E
F
L
A
F
E
S
V
L
C
T
P
D
Frog
Xenopus laevis
Q7ZY36
473
52338
Zebra Danio
Brachydanio rerio
NP_997947
682
75371
H48
V
Q
R
Y
L
G
L
H
T
Q
L
H
F
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA73
695
76736
F66
V
R
K
F
L
G
L
F
S
E
S
A
F
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21153
707
78652
Y88
I
R
G
Y
L
G
L
Y
T
E
E
N
Y
N
K
Sea Urchin
Strong. purpuratus
XP_785145
691
77086
Q75
I
R
G
Y
L
N
M
Q
P
E
R
N
Y
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12482
902
104286
F91
S
K
F
T
D
H
S
F
N
L
N
Q
I
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.8
97.7
N.A.
96.7
72.5
N.A.
85.5
83.1
20.2
77.5
N.A.
57.1
N.A.
52
60.7
Protein Similarity:
100
99.4
99.8
98.9
N.A.
98.5
81.8
N.A.
89.8
89.3
34.2
86.9
N.A.
73.3
N.A.
68.7
74.1
P-Site Identity:
100
100
100
100
N.A.
100
40
N.A.
13.3
13.3
0
60
N.A.
33.3
N.A.
46.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
20
33.3
0
73.3
N.A.
73.3
N.A.
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
36
0
0
0
0
15
% D
% Glu:
8
0
8
0
0
0
0
8
0
29
8
0
0
0
0
% E
% Phe:
8
0
8
15
0
0
8
22
0
0
0
0
15
0
0
% F
% Gly:
0
0
15
0
0
58
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% H
% Ile:
15
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
8
0
0
8
0
0
0
0
0
0
0
8
15
% K
% Leu:
0
0
0
0
86
0
58
0
0
8
15
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
43
0
8
50
0
72
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
36
0
8
15
58
% P
% Gln:
0
50
0
0
0
0
0
8
0
8
0
15
0
0
0
% Q
% Arg:
0
22
58
0
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
22
0
22
0
36
0
8
% S
% Thr:
0
8
0
8
0
0
0
0
15
0
0
0
8
0
0
% T
% Val:
58
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
65
0
0
0
43
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _