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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A12
All Species:
25.15
Human Site:
Y656
Identified Species:
42.56
UniProt:
O75746
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75746
NP_003696.2
678
74762
Y656
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Chimpanzee
Pan troglodytes
XP_001145847
680
74987
Y658
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Rhesus Macaque
Macaca mulatta
XP_001085208
678
74724
Y656
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Dog
Lupus familis
XP_535962
678
74780
Y656
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH59
677
74551
Y656
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Rat
Rattus norvegicus
XP_342641
717
78438
G691
L
A
V
A
T
F
A
G
I
E
N
K
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514496
680
74679
Y658
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Chicken
Gallus gallus
XP_428938
642
70679
N619
A
T
F
A
G
I
E
N
K
F
G
L
Y
L
P
Frog
Xenopus laevis
Q7ZY36
473
52338
K452
G
I
A
P
N
F
L
K
V
L
P
A
V
S
I
Zebra Danio
Brachydanio rerio
NP_997947
682
75371
H658
V
E
N
K
F
G
L
H
L
P
K
F
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA73
695
76736
F673
L
A
G
V
E
S
K
F
G
L
Y
L
P
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21153
707
78652
Y682
N
P
D
H
V
G
G
Y
K
L
A
A
A
T
F
Sea Urchin
Strong. purpuratus
XP_785145
691
77086
F669
M
Q
L
A
V
A
T
F
S
G
V
E
T
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12482
902
104286
S868
H
A
N
Y
Y
Y
K
S
C
Q
I
A
K
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.8
97.7
N.A.
96.7
72.5
N.A.
85.5
83.1
20.2
77.5
N.A.
57.1
N.A.
52
60.7
Protein Similarity:
100
99.4
99.8
98.9
N.A.
98.5
81.8
N.A.
89.8
89.3
34.2
86.9
N.A.
73.3
N.A.
68.7
74.1
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
13.3
80
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
6.6
20
93.3
N.A.
13.3
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
8
22
0
8
8
0
0
0
8
22
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
0
0
8
0
8
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
8
0
50
15
0
15
0
8
0
50
8
0
29
% F
% Gly:
8
0
8
0
8
58
8
8
8
8
8
0
0
8
0
% G
% His:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
43
8
0
0
0
8
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
0
0
50
0
0
15
8
15
0
50
8
58
8
0
% K
% Leu:
15
0
8
0
0
0
58
0
50
22
0
15
0
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
58
0
8
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
50
8
0
8
0
50
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
8
0
8
8
0
0
0
0
58
8
% S
% Thr:
0
8
0
0
8
0
8
0
0
0
0
0
8
15
0
% T
% Val:
8
0
8
8
15
0
0
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
0
50
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _