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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3C2G
All Species:
4.55
Human Site:
T62
Identified Species:
12.5
UniProt:
O75747
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75747
NP_004561.3
1444
165650
T62
E
S
E
I
D
E
N
T
F
F
V
P
T
A
P
Chimpanzee
Pan troglodytes
XP_514126
1613
182398
S115
S
Q
G
P
Q
P
G
S
D
P
W
P
K
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536097
1864
208404
P115
S
Q
G
S
Q
P
G
P
D
P
W
P
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
O70167
1506
171561
T62
E
S
E
K
E
E
D
T
Y
F
V
P
D
A
P
Rat
Rattus norvegicus
O70173
1505
170957
C62
E
D
E
K
E
G
T
C
F
V
P
D
T
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510027
1689
189289
Q210
A
T
T
P
F
L
P
Q
G
S
L
P
V
Y
R
Chicken
Gallus gallus
XP_416412
1416
161392
P62
G
S
S
H
L
H
H
P
E
E
H
F
F
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665474
1055
120188
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524028
1876
210456
P162
Q
R
P
T
A
A
Q
P
T
P
Y
G
M
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
N.A.
31
N.A.
70.1
68.6
N.A.
31.7
57.1
N.A.
33.5
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
52.2
N.A.
47.6
N.A.
81.1
80.4
N.A.
49.3
71.6
N.A.
49.3
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
66.6
26.6
N.A.
6.6
6.6
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
6.6
N.A.
86.6
33.3
N.A.
20
20
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
12
0
0
0
0
0
0
0
23
12
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
12
0
12
0
23
0
0
12
12
0
0
% D
% Glu:
34
0
34
0
23
23
0
0
12
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
23
23
0
12
12
0
0
% F
% Gly:
12
0
23
0
0
12
23
0
12
0
0
12
0
23
0
% G
% His:
0
0
0
12
0
12
12
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
0
0
0
0
0
0
23
0
0
% K
% Leu:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
23
0
23
12
34
0
34
12
56
0
12
23
% P
% Gln:
12
23
0
0
23
0
12
12
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
23
34
12
12
0
0
0
12
0
12
0
0
0
12
34
% S
% Thr:
0
12
12
12
0
0
12
23
12
0
0
0
23
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
23
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
12
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _