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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHBDL1 All Species: 4.55
Human Site: S138 Identified Species: 8.33
UniProt: O75783 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75783 NP_003952.1 438 48314 S138 D L I S S K R S S S F K R A I
Chimpanzee Pan troglodytes XP_510716 438 48282 S138 D L I S S K R S S S F K R A I
Rhesus Macaque Macaca mulatta XP_001118514 374 41208 L112 D P A K L D M L V A L A Q S N
Dog Lupus familis XP_547213 367 40981 E105 F V R Y V A Y E I L P R E V D
Cat Felis silvestris
Mouse Mus musculus Q8VC82 373 41768 E111 F V R Y V A Y E I L P C E V D
Rat Rattus norvegicus O88779 164 17644
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517314 200 21905
Chicken Gallus gallus XP_426761 278 30806 F16 L D P E N T G F I G V E T F A
Frog Xenopus laevis NP_001086211 372 41859 E110 F V R Y V A Y E I L P G E M E
Zebra Danio Brachydanio rerio NP_001017556 306 34504 E44 L V R H V A Y E T L P R E V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20350 355 39311 L93 E S E D I G L L K Y V H R Q H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19821 356 40615 Q94 D P I M S D S Q K I E V H S Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80946 740 82313 K133 L G A S G S G K S T L I D A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 82.1 81.9 N.A. 82.1 37.2 N.A. 42.4 56.6 70.7 41.5 N.A. 28.3 N.A. 22.8 N.A.
Protein Similarity: 100 99.5 82.4 82.8 N.A. 83.5 37.4 N.A. 44 59.3 77.8 54.5 N.A. 44.2 N.A. 40.1 N.A.
P-Site Identity: 100 100 6.6 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 100 26.6 13.3 N.A. 6.6 0 N.A. 0 13.3 6.6 20 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 31 0 0 0 8 0 8 0 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 31 8 0 8 0 16 0 0 0 0 0 0 8 0 24 % D
% Glu: 8 0 8 8 0 0 0 31 0 0 8 8 31 0 8 % E
% Phe: 24 0 0 0 0 0 0 8 0 0 16 0 0 8 0 % F
% Gly: 0 8 0 0 8 8 16 0 0 8 0 8 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 8 % H
% Ile: 0 0 24 0 8 0 0 0 31 8 0 8 0 0 16 % I
% Lys: 0 0 0 8 0 16 0 8 16 0 0 16 0 0 0 % K
% Leu: 24 16 0 0 8 0 8 16 0 31 16 0 0 0 8 % L
% Met: 0 0 0 8 0 0 8 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 16 8 0 0 0 0 0 0 0 31 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % Q
% Arg: 0 0 31 0 0 0 16 0 0 0 0 16 24 0 0 % R
% Ser: 0 8 0 24 24 8 8 16 24 16 0 0 0 16 0 % S
% Thr: 0 0 0 0 0 8 0 0 8 8 0 0 8 0 0 % T
% Val: 0 31 0 0 31 0 0 0 8 0 16 8 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 24 0 0 31 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _