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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6AP2 All Species: 27.27
Human Site: S253 Identified Species: 60
UniProt: O75787 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75787 NP_005756.2 350 39008 S253 K F A D D M Y S L Y G G N A V
Chimpanzee Pan troglodytes XP_521010 453 50504 S356 K F A D D M Y S L Y G G N A V
Rhesus Macaque Macaca mulatta XP_001093417 456 49956 N359 K F A D D M Y N L Y G G N A V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CYN9 350 39073 S254 K F A D D M Y S L Y G G N A V
Rat Rattus norvegicus Q6AXS4 350 39063 S254 K F A D D M Y S L Y G G N A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513006 404 45197 S307 K F A D E M S S L Y G G N A V
Chicken Gallus gallus NP_001025972 333 37458 Y236 Q K F A D E M Y N L Y G G N A
Frog Xenopus laevis NP_001080880 348 38928 S251 K F A D D M Y S I Y G G N A I
Zebra Danio Brachydanio rerio NP_998188 386 43065 S289 K F A D D V S S V Y G N N A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624608 317 35295 Q226 F I Q A Y D G Q V L I V A F T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200073 347 38411 E244 Q W G R D M V E L Y G E D L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 75.8 N.A. N.A. 94 92.5 N.A. 73.2 68.8 69.4 62.4 N.A. N.A. 30.5 N.A. 31.7
Protein Similarity: 100 77.2 76.7 N.A. N.A. 97.4 96.2 N.A. 80.6 82 84.8 77.4 N.A. N.A. 49.4 N.A. 56
P-Site Identity: 100 100 93.3 N.A. N.A. 100 100 N.A. 86.6 13.3 86.6 73.3 N.A. N.A. 0 N.A. 33.3
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 93.3 20 100 86.6 N.A. N.A. 6.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 73 19 0 0 0 0 0 0 0 0 10 73 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 73 82 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 10 10 0 10 0 0 0 10 0 0 0 % E
% Phe: 10 73 10 0 0 0 0 0 0 0 0 0 0 10 10 % F
% Gly: 0 0 10 0 0 0 10 0 0 0 82 73 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 10 0 10 0 0 0 10 % I
% Lys: 73 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 64 19 0 0 0 10 0 % L
% Met: 0 0 0 0 0 73 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 10 0 0 10 73 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 64 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 10 10 0 19 0 0 10 0 0 64 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 55 10 0 82 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _