KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
22.12
Human Site:
S115
Identified Species:
37.44
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
S115
R
V
K
Y
N
L
N
S
L
S
H
D
T
A
T
Chimpanzee
Pan troglodytes
XP_512415
299
33388
S115
R
V
K
Y
N
L
N
S
L
S
H
D
T
A
T
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
S116
R
V
K
Y
N
L
N
S
L
S
H
D
T
A
T
Dog
Lupus familis
XP_542041
299
33429
S116
R
V
K
Y
N
L
N
S
L
S
H
D
T
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
S116
R
V
K
Y
N
L
N
S
L
S
H
D
T
A
A
Rat
Rattus norvegicus
Q5U209
301
33267
S116
R
V
K
Y
N
L
N
S
M
S
H
D
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
A116
R
A
K
Y
N
L
N
A
L
S
H
D
A
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
E161
R
S
K
C
S
L
N
E
V
S
M
D
S
A
M
Honey Bee
Apis mellifera
XP_396289
317
35722
E133
R
V
K
T
S
L
N
E
V
S
M
N
S
A
I
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
E112
R
Q
K
Y
S
L
N
E
V
S
H
E
A
A
I
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
A139
R
N
K
H
S
L
N
A
V
S
M
D
S
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
E101
K
N
K
T
N
L
N
E
I
S
H
N
S
A
M
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
E129
T
R
N
Y
N
L
N
E
Q
A
H
D
V
T
M
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
Q140
A
Q
I
Y
N
L
N
Q
Q
A
M
D
A
T
I
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
46.6
46.6
53.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
66.6
73.3
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
15
0
15
0
0
22
86
15
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
79
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
36
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
72
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
36
% I
% Lys:
8
0
86
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
100
0
0
43
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
29
0
0
0
22
% M
% Asn:
0
15
8
0
72
0
100
0
0
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
8
15
0
0
0
0
0
0
% Q
% Arg:
79
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
29
0
0
43
0
86
0
0
29
0
0
% S
% Thr:
8
0
0
15
0
0
0
0
0
0
0
0
43
15
29
% T
% Val:
0
50
0
0
0
0
0
0
29
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _