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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
9.09
Human Site:
S156
Identified Species:
15.38
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
S156
Y
Q
A
R
L
Q
Q
S
F
P
G
I
E
V
T
Chimpanzee
Pan troglodytes
XP_512415
299
33388
S156
Y
Q
A
R
L
Q
Q
S
F
P
G
I
E
V
T
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
S157
Y
Q
A
R
L
Q
Q
S
F
P
G
I
E
V
T
Dog
Lupus familis
XP_542041
299
33429
R157
Y
Q
E
R
L
Q
Q
R
F
P
G
I
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
H157
Y
Q
A
R
L
Q
Q
H
F
P
G
I
E
V
T
Rat
Rattus norvegicus
Q5U209
301
33267
R157
Y
Q
A
R
L
Q
Q
R
F
P
G
I
E
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
R157
Y
Q
D
K
L
S
Q
R
F
P
G
V
E
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
R202
Y
Q
E
K
L
L
K
R
F
P
S
F
K
I
T
Honey Bee
Apis mellifera
XP_396289
317
35722
I174
Y
Q
A
K
L
E
Q
I
F
P
D
I
K
I
T
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
L153
Y
Q
A
K
L
E
K
L
F
P
G
I
S
I
C
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
L180
Y
Q
D
K
L
K
G
L
F
P
D
L
D
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
R142
Y
R
I
K
L
S
E
R
F
P
S
I
K
F
V
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
R170
Y
Q
K
K
L
E
Q
R
F
P
G
V
K
F
T
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
V181
Y
Q
K
K
L
E
R
V
F
P
T
A
K
I
T
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
40
60
53.3
40
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
66.6
86.6
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
33.3
53.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
60
80
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
15
0
8
0
0
% D
% Glu:
0
0
15
0
0
29
8
0
0
0
0
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
8
0
15
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
65
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
0
65
0
36
0
% I
% Lys:
0
0
15
58
0
8
15
0
0
0
0
0
36
0
0
% K
% Leu:
0
0
0
0
100
8
0
15
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
0
93
0
0
0
43
65
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
43
0
0
8
43
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
15
0
22
0
0
15
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
86
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
15
0
50
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _