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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
19.09
Human Site:
T269
Identified Species:
32.31
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
T269
Q
E
G
L
R
K
I
T
S
Y
F
L
N
E
G
Chimpanzee
Pan troglodytes
XP_512415
299
33388
T269
Q
E
G
L
R
K
I
T
S
Y
F
L
N
E
G
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
T270
Q
E
G
L
R
K
I
T
S
Y
F
L
N
E
G
Dog
Lupus familis
XP_542041
299
33429
M270
Q
E
G
P
G
R
I
M
S
Y
F
S
K
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
I270
D
P
E
R
P
G
K
I
T
S
Y
F
S
Q
G
Rat
Rattus norvegicus
Q5U209
301
33267
I270
D
P
E
G
P
G
R
I
T
S
Y
F
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
N270
E
K
A
A
A
R
Q
N
N
T
S
V
L
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
L315
P
K
Y
A
G
T
K
L
T
K
F
F
K
G
T
Honey Bee
Apis mellifera
XP_396289
317
35722
S285
N
P
G
E
Q
K
I
S
S
F
F
A
K
S
P
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
T267
K
S
Q
S
K
R
M
T
S
W
M
V
P
K
N
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
S293
E
A
A
K
G
T
A
S
L
L
S
F
F
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
S261
K
R
Q
A
K
L
S
S
F
G
F
K
T
C
E
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
R275
E
E
Q
Y
M
D
S
R
K
N
A
A
Q
K
T
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
T287
E
E
E
T
Q
K
L
T
D
F
F
M
A
K
R
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
100
46.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
33.3
13.3
0
P-Site Similarity:
100
100
100
53.3
N.A.
33.3
33.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
20
53.3
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
22
8
0
8
0
0
0
8
15
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
15
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
29
43
22
8
0
0
0
0
0
0
0
0
0
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
15
58
29
8
0
0
% F
% Gly:
0
0
36
8
22
15
0
0
0
8
0
0
0
15
36
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
36
15
0
0
0
0
0
0
0
% I
% Lys:
15
15
0
8
15
36
15
0
8
8
0
8
22
22
0
% K
% Leu:
0
0
0
22
0
8
8
8
8
8
0
22
8
0
0
% L
% Met:
0
0
0
0
8
0
8
8
0
0
8
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
8
0
0
22
0
8
% N
% Pro:
8
22
0
8
15
0
0
0
0
0
0
0
8
0
22
% P
% Gln:
29
0
22
0
15
0
8
0
0
0
0
0
8
15
0
% Q
% Arg:
0
8
0
8
22
22
8
8
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
8
0
0
15
22
43
15
15
8
15
15
0
% S
% Thr:
0
0
0
8
0
15
0
36
22
8
0
0
8
0
15
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
29
15
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _