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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2A
All Species:
10.23
Human Site:
T297
Identified Species:
17.31
UniProt:
O75792
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75792
NP_006388.2
299
33395
T297
E
R
G
L
E
S
A
T
S
L
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_512415
299
33388
T297
E
R
G
L
E
S
A
T
S
L
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001109423
300
33560
T298
E
R
G
L
E
S
A
T
S
L
_
_
_
_
_
Dog
Lupus familis
XP_542041
299
33429
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY8
301
33494
A298
Q
E
R
G
L
E
A
A
S
S
L
_
_
_
_
Rat
Rattus norvegicus
Q5U209
301
33267
A298
Q
E
R
G
L
E
T
A
T
S
L
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956520
307
34193
E298
D
I
H
R
F
F
T
E
R
K
L
K
S
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPP5
347
38732
S343
F
K
Q
R
H
L
E
S
V
M
E
F
_
_
_
Honey Bee
Apis mellifera
XP_396289
317
35722
N313
F
T
E
R
C
L
F
N
T
S
T
L
_
_
_
Nematode Worm
Caenorhab. elegans
Q9U6P6
297
33173
L295
E
R
H
M
S
N
I
L
T
F
_
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_782683
324
35831
V321
N
E
R
D
L
K
Q
V
T
A
M
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEZ6
296
33059
K289
C
K
F
L
Q
A
R
K
I
Q
Q
L
T
Q
F
Baker's Yeast
Sacchar. cerevisiae
P53942
307
34857
D303
R
K
R
L
R
T
L
D
N
W
Y
R
_
_
_
Red Bread Mold
Neurospora crassa
Q9P5X8
317
34608
E315
F
G
A
P
A
G
V
E
C
F
_
_
_
_
_
Conservation
Percent
Protein Identity:
100
98.3
95.6
86.2
N.A.
86.3
85.3
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
43.5
47.3
48.8
45.9
Protein Similarity:
100
99
97
90.9
N.A.
91.3
91.3
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
58.7
66.5
63.8
65.1
P-Site Identity:
100
100
100
0
N.A.
18.1
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
0
20
0
P-Site Similarity:
100
100
100
0
N.A.
27.2
18.1
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
25
8.3
50
9
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.8
38.7
39.4
Protein Similarity:
N.A.
N.A.
N.A.
64.5
57.3
56.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
8.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
41.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
29
15
0
8
0
0
0
0
0
% A
% Cys:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
29
22
8
0
22
15
8
15
0
0
8
0
0
0
0
% E
% Phe:
22
0
8
0
8
8
8
0
0
15
0
8
0
0
8
% F
% Gly:
0
8
22
15
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
8
0
0
0
0
8
0
% I
% Lys:
0
22
0
0
0
8
0
8
0
8
0
8
0
0
0
% K
% Leu:
0
0
0
36
22
15
8
8
0
22
22
15
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
8
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
8
0
8
0
8
0
0
8
8
0
0
8
0
% Q
% Arg:
8
29
29
22
8
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
8
22
0
8
29
22
0
0
8
0
0
% S
% Thr:
0
8
0
0
0
8
15
22
29
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
36
58
79
79
79
% _