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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC123
All Species:
39.7
Human Site:
S299
Identified Species:
72.78
UniProt:
O75794
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75794
NP_006014.2
336
39135
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Chimpanzee
Pan troglodytes
XP_001136775
336
39049
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Rhesus Macaque
Macaca mulatta
XP_001083055
336
39029
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Dog
Lupus familis
XP_535189
441
49449
S404
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CII2
336
38798
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
F
G
L
Rat
Rattus norvegicus
Q62834
336
38794
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515736
345
39574
S308
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Chicken
Gallus gallus
XP_424021
335
38852
S298
S
Q
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Frog
Xenopus laevis
Q641C9
338
39577
S298
R
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Zebra Danio
Brachydanio rerio
Q6PC40
348
39869
S300
S
E
V
T
V
Q
P
S
P
C
L
S
Y
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782770
317
36601
F285
A
Y
S
M
P
S
D
F
L
D
L
R
S
G
T
Poplar Tree
Populus trichocarpa
XP_002310498
336
38412
L306
T
A
V
P
Q
D
Y
L
D
T
G
P
G
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05791
360
41833
H319
S
K
E
H
S
E
N
H
V
P
Q
D
L
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
73
N.A.
92.2
93.1
N.A.
85.2
86.6
79.5
69.2
N.A.
N.A.
N.A.
N.A.
43.4
Protein Similarity:
100
99.6
99.4
73.9
N.A.
95.5
95.2
N.A.
88.9
91.6
88.1
80.7
N.A.
N.A.
N.A.
N.A.
62.5
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
100
93.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
36.9
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
56.2
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
8
8
0
8
0
0
0
% D
% Glu:
0
70
8
0
0
8
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
8
24
8
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
85
0
8
0
70
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
77
0
77
8
0
8
0
0
0
% P
% Gln:
0
8
0
0
8
77
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
62
0
% R
% Ser:
77
0
8
0
8
8
0
77
0
0
0
77
8
8
0
% S
% Thr:
8
0
0
77
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
0
85
0
77
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
70
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _