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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC123 All Species: 38.79
Human Site: T141 Identified Species: 71.11
UniProt: O75794 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75794 NP_006014.2 336 39135 T141 F K S S D F I T R D F T Q P F
Chimpanzee Pan troglodytes XP_001136775 336 39049 T141 F K S S D F I T R D F T Q P F
Rhesus Macaque Macaca mulatta XP_001083055 336 39029 T141 F K S S D F I T R D F T Q P F
Dog Lupus familis XP_535189 441 49449 T246 F K S S D F I T R D F T Q P F
Cat Felis silvestris
Mouse Mus musculus Q8CII2 336 38798 T141 F K S S D F I T H D F T Q P F
Rat Rattus norvegicus Q62834 336 38794 T141 F K S S D F I T H D F T Q P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515736 345 39574 T149 F K S S D F I T H D F T Q P F
Chicken Gallus gallus XP_424021 335 38852 T140 F K S S D F I T R D L T Q P F
Frog Xenopus laevis Q641C9 338 39577 T142 F K S S D F V T H D F T Q P F
Zebra Danio Brachydanio rerio Q6PC40 348 39869 T142 F K S S D F I T H D L T Q P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782770 317 36601 E141 F T L C D E T E Q A G Q V Q Y
Poplar Tree Populus trichocarpa XP_002310498 336 38412 V147 L R S S D S L V H D L C H A Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05791 360 41833 M161 L N A S N Y I M H D L Q R A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.1 73 N.A. 92.2 93.1 N.A. 85.2 86.6 79.5 69.2 N.A. N.A. N.A. N.A. 43.4
Protein Similarity: 100 99.6 99.4 73.9 N.A. 95.5 95.2 N.A. 88.9 91.6 88.1 80.7 N.A. N.A. N.A. N.A. 62.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 86.6 86.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 86.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 36.9 N.A. N.A. N.A. 30.5 N.A.
Protein Similarity: 56.2 N.A. N.A. N.A. 50.5 N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 8 0 0 0 16 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 93 0 0 0 0 93 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % E
% Phe: 85 0 0 0 0 77 0 0 0 0 62 0 0 0 85 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 54 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 % I
% Lys: 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 0 8 0 0 0 8 0 0 0 31 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 77 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 16 77 8 0 % Q
% Arg: 0 8 0 0 0 0 0 0 39 0 0 0 8 0 0 % R
% Ser: 0 0 85 93 0 8 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 8 77 0 0 0 77 0 0 0 % T
% Val: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _