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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC123
All Species:
35.76
Human Site:
Y223
Identified Species:
65.56
UniProt:
O75794
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75794
NP_006014.2
336
39135
Y223
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Chimpanzee
Pan troglodytes
XP_001136775
336
39049
Y223
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Rhesus Macaque
Macaca mulatta
XP_001083055
336
39029
Y223
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Dog
Lupus familis
XP_535189
441
49449
Y328
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CII2
336
38798
Y223
F
F
K
E
H
L
Q
Y
K
F
L
D
E
D
F
Rat
Rattus norvegicus
Q62834
336
38794
Y223
F
F
K
E
H
L
Q
Y
K
F
L
D
E
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515736
345
39574
Y231
F
F
Q
K
H
I
Q
Y
K
F
L
D
E
D
F
Chicken
Gallus gallus
XP_424021
335
38852
Y222
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Frog
Xenopus laevis
Q641C9
338
39577
Q219
K
S
I
Q
Y
F
F
Q
E
H
I
Q
Y
N
F
Zebra Danio
Brachydanio rerio
Q6PC40
348
39869
Y224
F
F
R
D
N
I
Q
Y
Q
F
P
D
E
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782770
317
36601
G209
F
H
D
R
Y
V
A
G
L
F
K
E
Q
H
Y
Poplar Tree
Populus trichocarpa
XP_002310498
336
38412
Q230
F
F
T
E
N
V
R
Q
K
F
E
S
E
N
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05791
360
41833
P242
I
V
H
D
V
V
L
P
K
F
P
D
K
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
73
N.A.
92.2
93.1
N.A.
85.2
86.6
79.5
69.2
N.A.
N.A.
N.A.
N.A.
43.4
Protein Similarity:
100
99.6
99.4
73.9
N.A.
95.5
95.2
N.A.
88.9
91.6
88.1
80.7
N.A.
N.A.
N.A.
N.A.
62.5
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
100
6.6
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
40
86.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
36.9
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
56.2
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
0
0
0
0
0
77
0
70
0
% D
% Glu:
0
0
0
24
0
0
0
0
8
0
8
8
77
0
0
% E
% Phe:
85
77
0
0
0
8
8
0
0
93
0
0
0
0
85
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
8
0
62
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
8
0
8
0
0
54
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
54
47
0
0
0
0
77
0
8
0
8
0
0
% K
% Leu:
0
0
0
0
0
16
8
0
8
0
62
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
0
0
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
70
16
8
0
0
8
8
0
0
% Q
% Arg:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
24
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
70
0
0
0
0
8
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _