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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOLH All Species: 9.7
Human Site: S237 Identified Species: 17.78
UniProt: O75808 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75808 NP_005623.1 1086 117314 S237 P P F S P F S S T L Q N N P V
Chimpanzee Pan troglodytes XP_001172892 461 48848
Rhesus Macaque Macaca mulatta XP_001085465 1086 117314 S237 P P F S P F S S T L Q N N P V
Dog Lupus familis XP_852291 1070 115743 P222 P S F G P F S P T L Q N N P V
Cat Felis silvestris
Mouse Mus musculus Q9JLG8 1095 118700 P244 P L F S P F S P T L Q N N P V
Rat Rattus norvegicus NP_001100460 1031 111871 E210 P G E G A E A E S P S T S Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505443 851 91287 E52 I L R L S V E E Q K W P C A R
Chicken Gallus gallus XP_414704 1016 111641 G173 P E V I T P A G F H M A P S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663893 1097 119990 S255 P F L P P S L S S L Q N N P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27398 1594 174295 K462 S S S S G S N K L Y E N E C V
Honey Bee Apis mellifera XP_624008 1343 150656 T415 P H S V G F S T K P K Y S Y I
Nematode Worm Caenorhab. elegans NP_741604 718 80894
Sea Urchin Strong. purpuratus XP_784619 1162 128497 F182 K P G T E F P F P E Q P T G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.2 86.2 N.A. 87.2 82.5 N.A. 59.2 73.7 N.A. 65.9 N.A. 33.5 37.2 25.4 29
Protein Similarity: 100 41.5 97.9 90.6 N.A. 90.6 85.7 N.A. 63.7 80.4 N.A. 73 N.A. 44.2 49.5 38.3 43.1
P-Site Identity: 100 0 100 80 N.A. 86.6 6.6 N.A. 0 6.6 N.A. 60 N.A. 20 20 0 20
P-Site Similarity: 100 0 100 80 N.A. 86.6 26.6 N.A. 0 13.3 N.A. 66.6 N.A. 33.3 46.6 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 16 0 0 0 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 8 8 8 16 0 8 8 0 8 0 0 % E
% Phe: 0 8 31 0 0 47 0 8 8 0 0 0 0 0 0 % F
% Gly: 0 8 8 16 16 0 0 8 0 0 0 0 0 8 8 % G
% His: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 0 8 8 8 8 0 0 0 0 % K
% Leu: 0 16 8 8 0 0 8 0 8 39 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 47 39 0 0 % N
% Pro: 62 24 0 8 39 8 8 16 8 16 0 16 8 39 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 47 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 16 16 31 8 16 39 24 16 0 8 0 16 8 0 % S
% Thr: 0 0 0 8 8 0 0 8 31 0 0 8 8 0 8 % T
% Val: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _