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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOLH All Species: 5.76
Human Site: S315 Identified Species: 10.56
UniProt: O75808 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75808 NP_005623.1 1086 117314 S315 S R V E A G S S T S G S D I I
Chimpanzee Pan troglodytes XP_001172892 461 48848
Rhesus Macaque Macaca mulatta XP_001085465 1086 117314 S315 S R V E A S S S A S G S D V I
Dog Lupus familis XP_852291 1070 115743 A302 V R C E A C G A A P G S D V I
Cat Felis silvestris
Mouse Mus musculus Q9JLG8 1095 118700 C325 P E S S P A R C E S C S D V I
Rat Rattus norvegicus NP_001100460 1031 111871 L290 G A S R L A E L L S G K E L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505443 851 91287 E126 G Q G P P G T E A A G G W T C
Chicken Gallus gallus XP_414704 1016 111641 D249 D T I N L V G D S V R F T P C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663893 1097 119990 P330 T S P P S W K P G S G G D V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27398 1594 174295 N536 I A S E S Q T N N N T G S G E
Honey Bee Apis mellifera XP_624008 1343 150656 S491 G C D I C G S S R S P P S L M
Nematode Worm Caenorhab. elegans NP_741604 718 80894
Sea Urchin Strong. purpuratus XP_784619 1162 128497 G256 P N P G E D D G T K K Y Q H R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.2 86.2 N.A. 87.2 82.5 N.A. 59.2 73.7 N.A. 65.9 N.A. 33.5 37.2 25.4 29
Protein Similarity: 100 41.5 97.9 90.6 N.A. 90.6 85.7 N.A. 63.7 80.4 N.A. 73 N.A. 44.2 49.5 38.3 43.1
P-Site Identity: 100 0 80 46.6 N.A. 26.6 13.3 N.A. 13.3 0 N.A. 26.6 N.A. 6.6 26.6 0 6.6
P-Site Similarity: 100 0 86.6 60 N.A. 33.3 33.3 N.A. 33.3 13.3 N.A. 46.6 N.A. 33.3 40 0 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 24 16 0 8 24 8 0 0 0 0 0 % A
% Cys: 0 8 8 0 8 8 0 8 0 0 8 0 0 0 16 % C
% Asp: 8 0 8 0 0 8 8 8 0 0 0 0 39 0 0 % D
% Glu: 0 8 0 31 8 0 8 8 8 0 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 24 0 8 8 0 24 16 8 8 0 47 24 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 8 8 0 0 0 0 0 0 0 0 0 8 39 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 8 8 0 0 0 % K
% Leu: 0 0 0 0 16 0 0 8 8 0 0 0 0 16 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 8 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 16 0 16 16 16 0 0 8 0 8 8 8 0 8 0 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 24 0 8 0 0 8 0 8 0 8 0 0 0 8 % R
% Ser: 16 8 24 8 16 8 24 24 8 47 0 31 16 0 0 % S
% Thr: 8 8 0 0 0 0 16 0 16 0 8 0 8 8 0 % T
% Val: 8 0 16 0 0 8 0 0 0 8 0 0 0 31 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _