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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOLH All Species: 29.39
Human Site: S492 Identified Species: 53.89
UniProt: O75808 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75808 NP_005623.1 1086 117314 S492 N V S F V D D S F P P G P E S
Chimpanzee Pan troglodytes XP_001172892 461 48848
Rhesus Macaque Macaca mulatta XP_001085465 1086 117314 S492 N V S F V D D S F P P G P E S
Dog Lupus familis XP_852291 1070 115743 S475 S V N F V D D S F P P G P E S
Cat Felis silvestris
Mouse Mus musculus Q9JLG8 1095 118700 S502 S V N F V D D S F P P G P A S
Rat Rattus norvegicus NP_001100460 1031 111871 T451 V T Q C R G A T P L R R R E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505443 851 91287 L286 G T K R L S V L E E E A V G A
Chicken Gallus gallus XP_414704 1016 111641 S424 K V N F V D D S F H P G P K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663893 1097 119990 S505 A V N F V D D S F P P G P R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27398 1594 174295 V725 Y S T A M A C V V C G G S K L
Honey Bee Apis mellifera XP_624008 1343 150656 S766 N E P F V D D S F P P A P K S
Nematode Worm Caenorhab. elegans NP_741604 718 80894 Q153 K K S I G S L Q F T K N G V K
Sea Urchin Strong. purpuratus XP_784619 1162 128497 S424 N T E F I D D S F P P T P D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.2 86.2 N.A. 87.2 82.5 N.A. 59.2 73.7 N.A. 65.9 N.A. 33.5 37.2 25.4 29
Protein Similarity: 100 41.5 97.9 90.6 N.A. 90.6 85.7 N.A. 63.7 80.4 N.A. 73 N.A. 44.2 49.5 38.3 43.1
P-Site Identity: 100 0 100 86.6 N.A. 80 13.3 N.A. 0 73.3 N.A. 80 N.A. 6.6 73.3 13.3 66.6
P-Site Similarity: 100 0 100 100 N.A. 93.3 20 N.A. 13.3 86.6 N.A. 86.6 N.A. 26.6 80 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 8 8 0 0 0 0 16 0 8 8 % A
% Cys: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 62 62 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 8 0 0 0 0 0 8 8 8 0 0 31 0 % E
% Phe: 0 0 0 62 0 0 0 0 70 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 8 8 0 0 0 0 8 54 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 8 8 0 0 0 0 0 0 0 8 0 0 24 8 % K
% Leu: 0 0 0 0 8 0 8 8 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 31 0 31 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 8 54 62 0 62 0 0 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 0 0 0 0 8 8 8 8 0 % R
% Ser: 16 8 24 0 0 16 0 62 0 0 0 0 8 0 70 % S
% Thr: 0 24 8 0 0 0 0 8 0 8 0 8 0 0 0 % T
% Val: 8 47 0 0 54 0 8 8 8 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _