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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP40
All Species:
12.42
Human Site:
S249
Identified Species:
39.05
UniProt:
O75818
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75818
NP_006629.2
363
41834
S249
D
W
L
G
A
V
F
S
N
V
D
L
N
N
E
Chimpanzee
Pan troglodytes
XP_527222
363
41628
S249
D
W
L
G
A
V
F
S
N
V
D
L
N
N
E
Rhesus Macaque
Macaca mulatta
XP_001095772
363
41547
S249
D
W
L
G
A
V
F
S
N
V
S
L
N
N
E
Dog
Lupus familis
XP_535875
363
41582
S249
D
W
L
G
A
V
F
S
R
A
D
L
T
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1F9
363
41528
C249
D
W
L
G
A
V
F
C
S
A
D
L
N
N
E
Rat
Rattus norvegicus
Q5BK64
363
41621
C249
D
W
L
G
A
V
F
C
N
A
D
L
N
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507727
336
38169
F233
M
D
N
Q
S
S
N
F
L
S
T
Y
C
C
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087634
359
41073
N245
D
W
L
G
A
V
S
N
S
I
D
C
D
N
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
95.8
86.5
N.A.
84.3
84
N.A.
66.1
N.A.
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97.5
93.3
N.A.
92.5
92.2
N.A.
78.5
N.A.
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
86.6
N.A.
0
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
88
0
0
0
0
38
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
0
0
13
13
13
0
% C
% Asp:
88
13
0
0
0
0
0
0
0
0
75
0
13
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% E
% Phe:
0
0
0
0
0
0
75
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
88
0
0
0
0
0
13
0
0
75
0
0
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
13
13
50
0
0
0
63
88
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
13
13
50
25
13
13
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
0
% T
% Val:
0
0
0
0
0
88
0
0
0
38
0
0
0
0
0
% V
% Trp:
0
88
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _