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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3G
All Species:
32.12
Human Site:
S247
Identified Species:
64.24
UniProt:
O75821
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75821
NP_003746.2
320
35611
S247
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Chimpanzee
Pan troglodytes
XP_001162623
321
35664
S248
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Rhesus Macaque
Macaca mulatta
XP_001104633
412
45884
S339
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Dog
Lupus familis
XP_854113
320
35548
S247
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1D1
320
35620
S247
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Rat
Rattus norvegicus
Q5RK09
320
35633
S247
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511404
168
18662
V96
T
T
T
V
S
D
D
V
S
M
T
F
I
T
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJI8
308
34347
S235
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Zebra Danio
Brachydanio rerio
Q6DRC4
293
32825
E221
I
R
V
T
N
L
S
E
D
T
R
E
T
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDM6
273
30508
S201
A
V
R
I
S
N
L
S
E
S
M
T
E
T
D
Honey Bee
Apis mellifera
XP_391934
285
31815
T213
I
S
N
L
S
E
S
T
T
D
A
D
L
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791582
297
32824
D224
R
V
T
N
L
S
E
D
T
R
E
S
D
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
77.6
99.3
N.A.
98.4
98.4
N.A.
46.2
N.A.
83.1
82.1
N.A.
41.8
48.1
N.A.
56.8
Protein Similarity:
100
99.6
77.6
99.6
N.A.
99
99
N.A.
49.3
N.A.
88.4
85.9
N.A.
57.1
61.5
N.A.
68.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
26.6
N.A.
100
0
N.A.
53.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
N.A.
100
6.6
N.A.
73.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
9
9
67
0
9
9
17
67
% D
% Glu:
0
0
0
0
0
9
9
9
67
0
9
9
67
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
59
0
9
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
9
9
67
0
0
0
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
0
0
9
9
9
67
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
9
67
0
0
0
0
0
0
9
9
59
0
0
0
% R
% Ser:
0
9
0
0
25
9
17
67
9
9
0
9
0
0
9
% S
% Thr:
67
9
17
9
59
0
0
9
17
9
67
9
9
75
0
% T
% Val:
0
17
9
67
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _