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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3G
All Species:
30.91
Human Site:
S266
Identified Species:
61.82
UniProt:
O75821
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75821
NP_003746.2
320
35611
S266
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Chimpanzee
Pan troglodytes
XP_001162623
321
35664
S267
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Rhesus Macaque
Macaca mulatta
XP_001104633
412
45884
S358
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Dog
Lupus familis
XP_854113
320
35548
S266
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1D1
320
35620
S266
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Rat
Rattus norvegicus
Q5RK09
320
35633
S266
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511404
168
18662
P115
N
C
Q
E
E
E
D
P
M
N
K
L
K
G
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJI8
308
34347
S254
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Zebra Danio
Brachydanio rerio
Q6DRC4
293
32825
R240
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDM6
273
30508
T220
V
K
K
I
G
P
H
T
K
M
Y
L
A
R
E
Honey Bee
Apis mellifera
XP_391934
285
31815
Y232
F
G
S
V
L
K
F
Y
L
A
K
D
K
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791582
297
32824
I243
P
F
G
A
I
Q
R
I
Y
L
A
Q
D
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
77.6
99.3
N.A.
98.4
98.4
N.A.
46.2
N.A.
83.1
82.1
N.A.
41.8
48.1
N.A.
56.8
Protein Similarity:
100
99.6
77.6
99.6
N.A.
99
99
N.A.
49.3
N.A.
88.4
85.9
N.A.
57.1
61.5
N.A.
68.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
100
0
N.A.
26.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
100
0
N.A.
66.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
9
9
9
67
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
9
9
9
59
% D
% Glu:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
9
% E
% Phe:
67
9
9
59
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
9
67
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
9
59
9
9
59
0
0
0
0
9
% I
% Lys:
0
9
9
0
0
9
0
0
9
0
17
0
25
67
9
% K
% Leu:
0
0
0
0
9
0
0
0
9
9
9
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
9
59
0
0
9
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
0
0
0
0
0
9
0
9
9
% Q
% Arg:
9
59
0
0
0
0
9
9
59
0
0
0
0
9
0
% R
% Ser:
0
0
9
0
9
59
9
59
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
9
9
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _