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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3G
All Species:
22.42
Human Site:
T41
Identified Species:
44.85
UniProt:
O75821
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75821
NP_003746.2
320
35611
T41
I
P
L
A
T
G
D
T
S
P
E
P
E
L
L
Chimpanzee
Pan troglodytes
XP_001162623
321
35664
T41
I
P
L
A
T
G
D
T
S
P
E
P
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001104633
412
45884
T133
I
P
L
A
T
G
D
T
S
P
E
P
E
L
L
Dog
Lupus familis
XP_854113
320
35548
T41
I
P
L
A
T
G
D
T
S
P
E
P
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1D1
320
35620
T41
I
P
L
P
T
G
D
T
S
P
E
P
E
L
L
Rat
Rattus norvegicus
Q5RK09
320
35633
T41
I
P
L
P
T
G
D
T
S
P
E
P
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511404
168
18662
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJI8
308
34347
D41
D
P
V
S
F
V
L
D
T
P
R
E
V
I
N
Zebra Danio
Brachydanio rerio
Q6DRC4
293
32825
V33
L
P
S
P
K
E
T
V
K
G
N
I
K
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDM6
273
30508
D13
T
S
W
A
D
E
V
D
A
D
Y
V
D
G
L
Honey Bee
Apis mellifera
XP_391934
285
31815
S25
G
G
A
L
P
P
P
S
E
S
Y
E
N
G
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791582
297
32824
K36
E
L
L
E
G
D
F
K
K
L
I
E
Y
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
77.6
99.3
N.A.
98.4
98.4
N.A.
46.2
N.A.
83.1
82.1
N.A.
41.8
48.1
N.A.
56.8
Protein Similarity:
100
99.6
77.6
99.6
N.A.
99
99
N.A.
49.3
N.A.
88.4
85.9
N.A.
57.1
61.5
N.A.
68.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
13.3
6.6
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
40
26.6
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
9
50
17
0
9
0
0
9
0
0
% D
% Glu:
9
0
0
9
0
17
0
0
9
0
50
25
50
0
0
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
9
9
0
0
9
50
0
0
0
9
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% I
% Lys:
0
0
0
0
9
0
0
9
17
0
0
0
9
9
0
% K
% Leu:
9
9
59
9
0
0
9
0
0
9
0
0
0
50
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% N
% Pro:
0
67
0
25
9
9
9
0
0
59
0
50
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
9
9
9
0
0
0
9
50
9
0
0
0
0
0
% S
% Thr:
9
0
0
0
50
0
9
50
9
0
0
0
0
9
0
% T
% Val:
0
0
9
0
0
9
9
9
0
0
0
9
9
0
17
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _