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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
26.36
Human Site:
S127
Identified Species:
41.43
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
S127
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
Chimpanzee
Pan troglodytes
XP_523193
60
6489
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
S127
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
Dog
Lupus familis
XP_544656
259
29118
S128
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
S132
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
Rat
Rattus norvegicus
A0JPM9
259
29169
S128
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
D135
K
K
L
Q
E
E
S
D
L
E
L
A
K
E
T
Chicken
Gallus gallus
Q5ZKA4
252
28706
E121
R
L
K
K
L
Q
E
E
S
D
L
E
L
A
K
Frog
Xenopus laevis
Q6INR1
255
29320
S123
Q
Q
K
L
Q
E
D
S
D
L
E
L
A
K
E
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
D118
K
Q
L
Q
E
D
S
D
L
E
L
A
K
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
S107
L
Q
K
I
Q
E
A
S
D
L
K
H
A
Q
E
Honey Bee
Apis mellifera
XP_397589
236
27385
D109
Q
R
L
Q
E
E
A
D
L
R
L
A
M
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
D114
Q
K
M
V
E
E
A
D
L
E
L
A
K
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
D102
Q
R
L
V
E
E
A
D
F
K
S
T
T
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
V96
K
L
R
M
Q
R
L
V
E
E
A
D
Y
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
13.3
13.3
80
0
N.A.
60
6.6
N.A.
13.3
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
26.6
26.6
93.3
26.6
N.A.
86.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
27
0
0
0
7
27
47
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
34
47
7
0
7
0
0
0
% D
% Glu:
0
0
0
0
34
74
40
7
7
27
40
7
0
34
47
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
47
54
7
0
0
0
0
0
7
7
0
20
40
7
% K
% Leu:
40
14
27
40
7
0
7
0
27
47
34
40
7
0
7
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
27
20
0
20
54
7
0
0
0
0
0
0
0
14
0
% Q
% Arg:
7
14
7
0
0
7
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
14
47
7
0
7
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
14
% T
% Val:
0
0
0
14
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _