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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF3J All Species: 50
Human Site: S152 Identified Species: 78.57
UniProt: O75822 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75822 NP_003749.2 258 29062 S152 I D A M N P S S R D D F T E F
Chimpanzee Pan troglodytes XP_523193 60 6489
Rhesus Macaque Macaca mulatta XP_001110624 258 29074 S152 I D A M N P S S R D D F T E F
Dog Lupus familis XP_544656 259 29118 S153 I D A M N P S S R D D F T E F
Cat Felis silvestris
Mouse Mus musculus Q66JS6 263 29467 S157 I D A M N P S S R D D F T E F
Rat Rattus norvegicus A0JPM9 259 29169 S153 I D A M N P S S R D D F T E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513268 266 29964 S160 I D A M N P I S R D D F T E F
Chicken Gallus gallus Q5ZKA4 252 28706 S146 I D A M N P S S K D D F T E F
Frog Xenopus laevis Q6INR1 255 29320 T148 I D A M N P S T R E D F T E F
Zebra Danio Brachydanio rerio Q7SXU0 249 28654 S143 I D A V S P S S K D D F T E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K550 236 26549 T132 L D A F N P E T K E E F K E F
Honey Bee Apis mellifera XP_397589 236 27385 T134 L D T I V P N T K E E F E Q Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783857 241 26703 T139 I D A M N P T T E E D F E E F
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150214 232 26006 S127 L D T F I P K S K S D F A E Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850918 225 25150 I121 E K S V D M L I P K S E S D F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.4 99.6 97.6 N.A. 95 96.9 N.A. 72.9 81.7 66.6 66.2 N.A. 38.7 39.9 N.A. 43
Protein Similarity: 100 22.8 99.6 98 N.A. 95.8 97.3 N.A. 80.4 90.6 79.4 82.9 N.A. 57.7 59.2 N.A. 63.5
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 93.3 93.3 86.6 80 N.A. 46.6 20 N.A. 66.6
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 93.3 100 100 100 N.A. 80 80 N.A. 86.6
Percent
Protein Identity: N.A. 33.7 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 53.4 N.A. 50 N.A. N.A.
P-Site Identity: N.A. 40 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 60 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 74 0 0 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 87 0 0 7 0 0 0 0 54 74 0 0 7 0 % D
% Glu: 7 0 0 0 0 0 7 0 7 27 14 7 14 80 0 % E
% Phe: 0 0 0 14 0 0 0 0 0 0 0 87 0 0 80 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 67 0 0 7 7 0 7 7 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 7 0 34 7 0 0 7 0 0 % K
% Leu: 20 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 60 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 67 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 87 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 7 0 54 60 0 7 7 0 7 0 0 % S
% Thr: 0 0 14 0 0 0 7 27 0 0 0 0 60 0 0 % T
% Val: 0 0 0 14 7 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _