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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
43.33
Human Site:
S173
Identified Species:
68.1
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
S173
K
I
T
Q
Y
E
K
S
L
Y
Y
A
S
F
L
Chimpanzee
Pan troglodytes
XP_523193
60
6489
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
S173
K
I
T
Q
Y
E
K
S
L
Y
Y
A
S
F
L
Dog
Lupus familis
XP_544656
259
29118
S174
K
I
T
Q
Y
E
K
S
L
Y
Y
A
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
S178
K
I
T
Q
Y
E
K
S
L
Y
Y
A
S
F
L
Rat
Rattus norvegicus
A0JPM9
259
29169
S174
K
I
T
Q
Y
E
K
S
L
Y
Y
A
S
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
S181
K
I
T
Q
Y
E
K
S
F
Y
Y
P
G
F
L
Chicken
Gallus gallus
Q5ZKA4
252
28706
S167
K
I
T
Q
Y
E
K
S
L
H
Y
A
S
F
L
Frog
Xenopus laevis
Q6INR1
255
29320
S169
K
I
T
Q
Y
E
R
S
L
Y
Y
P
G
F
L
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
S164
K
I
S
P
Y
E
K
S
I
H
Y
S
G
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
S153
K
V
G
Q
F
R
E
S
E
H
F
P
Q
F
V
Honey Bee
Apis mellifera
XP_397589
236
27385
H155
K
L
N
Q
F
A
K
H
S
E
F
P
L
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
S160
K
L
S
K
L
E
S
S
D
Y
Y
P
S
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
S148
K
L
R
P
Y
E
K
S
F
H
Y
M
A
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
F142
I
S
Q
R
L
V
P
F
E
K
S
F
H
Y
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
80
93.3
80
60
N.A.
26.6
26.6
N.A.
46.6
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
80
100
86.6
86.6
N.A.
66.6
46.6
N.A.
66.6
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
46.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
40
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
74
7
0
14
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
14
0
0
7
14
0
14
7
0
74
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
20
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
27
0
0
7
0
0
% H
% Ile:
7
60
0
0
0
0
0
0
7
0
0
0
0
0
7
% I
% Lys:
87
0
0
7
0
0
67
0
0
7
0
0
0
0
0
% K
% Leu:
0
20
0
0
14
0
0
0
47
0
0
0
7
14
74
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
14
0
0
7
0
0
0
0
34
0
0
0
% P
% Gln:
0
0
7
67
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
7
7
0
7
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
14
0
0
0
7
80
7
0
7
7
47
0
0
% S
% Thr:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
67
0
0
0
0
54
74
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _