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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF3J All Species: 17.27
Human Site: S20 Identified Species: 27.14
UniProt: O75822 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75822 NP_003749.2 258 29062 S20 S W D A D A F S V E D P V R K
Chimpanzee Pan troglodytes XP_523193 60 6489
Rhesus Macaque Macaca mulatta XP_001110624 258 29074 S20 S W D A D A F S V E D P V R K
Dog Lupus familis XP_544656 259 29118 S21 S W D A D T F S V E D P V R K
Cat Felis silvestris
Mouse Mus musculus Q66JS6 263 29467 S25 S W D A D T F S M E D P V R K
Rat Rattus norvegicus A0JPM9 259 29169 S21 S W D A D T F S M E D P V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513268 266 29964 C20 A G L P G G F C G G P L R R G
Chicken Gallus gallus Q5ZKA4 252 28706 V19 T F E V V E P V A K R L V P A
Frog Xenopus laevis Q6INR1 255 29320 N18 D F E A E D L N Q K G A A S G
Zebra Danio Brachydanio rerio Q7SXU0 249 28654 I18 S F E P E E P I K K A A V H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K550 236 26549 N24 P T A A A S V N K W E G E D E
Honey Bee Apis mellifera XP_397589 236 27385 E24 A I R S N K W E G E D E D E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783857 241 26703 N34 E G E D E E E N V K D D W A A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150214 232 26006 P20 V P V V K A E P L K N Q W A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850918 225 25150 W22 K V E L K S N W D D E D V D E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.4 99.6 97.6 N.A. 95 96.9 N.A. 72.9 81.7 66.6 66.2 N.A. 38.7 39.9 N.A. 43
Protein Similarity: 100 22.8 99.6 98 N.A. 95.8 97.3 N.A. 80.4 90.6 79.4 82.9 N.A. 57.7 59.2 N.A. 63.5
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. 13.3 6.6 6.6 13.3 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 0 100 93.3 N.A. 93.3 93.3 N.A. 20 33.3 40 40 N.A. 33.3 40 N.A. 40
Percent
Protein Identity: N.A. 33.7 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 53.4 N.A. 50 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 47 7 20 0 0 7 0 7 14 7 14 14 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 7 0 34 7 34 7 0 0 7 7 47 14 7 14 20 % D
% Glu: 7 0 34 0 20 20 14 7 0 40 14 7 7 7 14 % E
% Phe: 0 20 0 0 0 0 40 0 0 0 0 0 0 0 0 % F
% Gly: 0 14 0 0 7 7 0 0 14 7 7 7 0 0 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 14 7 0 0 14 34 0 0 0 0 34 % K
% Leu: 0 0 7 7 0 0 7 0 7 0 0 14 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 7 20 0 0 7 0 0 0 0 % N
% Pro: 7 7 0 14 0 0 14 7 0 0 7 34 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 7 0 7 40 0 % R
% Ser: 40 0 0 7 0 14 0 34 0 0 0 0 0 7 0 % S
% Thr: 7 7 0 0 0 20 0 0 0 0 0 0 0 0 0 % T
% Val: 7 7 7 14 7 0 7 7 27 0 0 0 54 0 0 % V
% Trp: 0 34 0 0 0 0 7 7 0 7 0 0 14 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _