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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF3J All Species: 41.82
Human Site: S202 Identified Species: 65.71
UniProt: O75822 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75822 NP_003749.2 258 29062 S202 D L K K I T N S L T V L C S E
Chimpanzee Pan troglodytes XP_523193 60 6489 V8 M T A I G Q A V L C N E K Q K
Rhesus Macaque Macaca mulatta XP_001110624 258 29074 S202 D L K K I T N S L T V L C S E
Dog Lupus familis XP_544656 259 29118 S203 D L K K I T N S L T V L C S E
Cat Felis silvestris
Mouse Mus musculus Q66JS6 263 29467 S207 D L K K I T N S L T V L C S E
Rat Rattus norvegicus A0JPM9 259 29169 S203 D L K K I T N S L T V L C S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513268 266 29964 S210 D L K K V T N S L T V L C S E
Chicken Gallus gallus Q5ZKA4 252 28706 S196 D L K K I T N S L T V L C S E
Frog Xenopus laevis Q6INR1 255 29320 S198 D L K K I N S S L T V L C F E
Zebra Danio Brachydanio rerio Q7SXU0 249 28654 S193 D L K K I N N S L T V L L S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K550 236 26549 N182 D I K K V K M N V E I L H S E
Honey Bee Apis mellifera XP_397589 236 27385 L184 H L K K V K T L I D N L L I E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783857 241 26703 S189 Q V R K I G S S L T A I A N E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150214 232 26006 S177 D A K D I S S S V T A I A N E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850918 225 25150 V171 K A A D V K D V A S S I T A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.4 99.6 97.6 N.A. 95 96.9 N.A. 72.9 81.7 66.6 66.2 N.A. 38.7 39.9 N.A. 43
Protein Similarity: 100 22.8 99.6 98 N.A. 95.8 97.3 N.A. 80.4 90.6 79.4 82.9 N.A. 57.7 59.2 N.A. 63.5
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 100 80 86.6 N.A. 40 33.3 N.A. 40
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 86.6 86.6 N.A. 73.3 46.6 N.A. 73.3
Percent
Protein Identity: N.A. 33.7 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 53.4 N.A. 50 N.A. N.A.
P-Site Identity: N.A. 40 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 73.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 14 0 0 0 7 0 7 0 14 0 14 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 54 0 0 % C
% Asp: 74 0 0 14 0 0 7 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 87 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 7 0 7 67 0 0 0 7 0 7 20 0 7 7 % I
% Lys: 7 0 80 80 0 20 0 0 0 0 0 0 7 0 7 % K
% Leu: 0 67 0 0 0 0 0 7 74 0 0 74 14 0 0 % L
% Met: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 14 54 7 0 0 14 0 0 14 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 7 20 74 0 7 7 0 0 60 0 % S
% Thr: 0 7 0 0 0 47 7 0 0 74 0 0 7 0 0 % T
% Val: 0 7 0 0 27 0 0 14 14 0 60 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _