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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
36.97
Human Site:
T157
Identified Species:
58.1
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
T157
P
S
S
R
D
D
F
T
E
F
G
K
L
L
K
Chimpanzee
Pan troglodytes
XP_523193
60
6489
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
T157
P
S
S
R
D
D
F
T
E
F
G
K
L
L
K
Dog
Lupus familis
XP_544656
259
29118
T158
P
S
S
R
D
D
F
T
E
F
G
K
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
T162
P
S
S
R
D
D
F
T
E
F
G
K
L
L
K
Rat
Rattus norvegicus
A0JPM9
259
29169
T158
P
S
S
R
D
D
F
T
E
F
G
K
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
T165
P
I
S
R
D
D
F
T
E
F
G
R
L
L
K
Chicken
Gallus gallus
Q5ZKA4
252
28706
T151
P
S
S
K
D
D
F
T
E
F
G
K
L
L
K
Frog
Xenopus laevis
Q6INR1
255
29320
T153
P
S
T
R
E
D
F
T
E
F
G
K
L
L
K
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
T148
P
S
S
K
D
D
F
T
E
F
E
R
L
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
K137
P
E
T
K
E
E
F
K
E
F
G
A
T
L
S
Honey Bee
Apis mellifera
XP_397589
236
27385
E139
P
N
T
K
E
E
F
E
Q
Y
G
S
V
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
E144
P
T
T
E
E
D
F
E
E
F
G
K
L
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
A132
P
K
S
K
S
D
F
A
E
Y
A
E
L
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
S126
M
L
I
P
K
S
E
S
D
F
L
D
Y
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
86.6
93.3
86.6
80
N.A.
40
26.6
N.A.
66.6
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
66.6
80
N.A.
86.6
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
7
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
54
74
0
0
7
0
0
7
0
0
0
% D
% Glu:
0
7
0
7
27
14
7
14
80
0
7
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
87
0
0
80
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
74
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
7
0
34
7
0
0
7
0
0
0
54
0
0
67
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
7
0
74
80
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
87
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
47
0
0
0
0
0
0
0
14
0
0
0
% R
% Ser:
0
54
60
0
7
7
0
7
0
0
0
7
0
0
7
% S
% Thr:
0
7
27
0
0
0
0
60
0
0
0
0
7
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
14
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _