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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
28.79
Human Site:
T235
Identified Species:
45.24
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
T235
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Chimpanzee
Pan troglodytes
XP_523193
60
6489
M38
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Y
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
T235
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Dog
Lupus familis
XP_544656
259
29118
T236
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
T240
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Rat
Rattus norvegicus
A0JPM9
259
29169
T236
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
T243
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Chicken
Gallus gallus
Q5ZKA4
252
28706
T229
P
G
G
G
L
K
A
T
M
K
D
D
L
A
D
Frog
Xenopus laevis
Q6INR1
255
29320
N232
P
G
G
G
L
K
G
N
M
K
D
Y
L
E
D
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
K226
P
G
G
G
L
K
A
K
M
K
D
D
L
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
T213
K
G
K
V
T
L
R
T
E
N
D
D
I
D
G
Honey Bee
Apis mellifera
XP_397589
236
27385
I214
K
G
K
A
K
L
K
I
E
G
D
N
T
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
G219
K
A
V
L
A
G
S
G
K
S
A
K
K
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
H207
G
A
K
K
K
Q
L
H
I
E
K
G
D
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
Q201
K
K
S
G
K
K
K
Q
L
H
V
D
K
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
100
100
73.3
93.3
N.A.
26.6
13.3
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
73.3
93.3
N.A.
33.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
7
7
54
0
0
0
7
0
7
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
80
67
7
27
80
% D
% Glu:
0
0
0
0
0
0
0
0
14
7
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
80
67
67
0
7
7
7
0
7
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% I
% Lys:
27
7
20
7
27
67
14
7
14
60
7
7
14
0
0
% K
% Leu:
0
0
0
14
60
14
7
0
7
0
0
7
60
7
7
% L
% Met:
0
0
0
0
0
0
0
7
60
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
7
0
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
7
54
0
0
0
0
7
0
0
% T
% Val:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _