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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
36.97
Human Site:
Y250
Identified Species:
58.1
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
Y250
Y
G
G
Y
D
G
G
Y
V
Q
D
Y
E
D
F
Chimpanzee
Pan troglodytes
XP_523193
60
6489
V53
G
G
Y
D
G
G
Y
V
Q
D
Y
E
D
F
M
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
Y250
Y
G
G
Y
D
G
G
Y
V
Q
D
Y
E
D
F
Dog
Lupus familis
XP_544656
259
29118
Y251
Y
G
G
Y
D
G
G
Y
V
Q
D
Y
E
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
Y255
Y
G
G
Y
E
G
G
Y
V
Q
D
Y
E
D
F
Rat
Rattus norvegicus
A0JPM9
259
29169
Y251
Y
G
G
Y
D
G
G
Y
V
Q
D
Y
E
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
Y258
Y
G
G
Y
D
G
G
Y
V
Q
D
F
E
D
F
Chicken
Gallus gallus
Q5ZKA4
252
28706
Y244
Y
G
G
Y
D
G
E
Y
V
Q
E
F
E
D
F
Frog
Xenopus laevis
Q6INR1
255
29320
Y247
Y
G
G
M
D
E
G
Y
G
R
E
F
D
D
F
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
Y241
Y
G
G
F
D
G
G
Y
A
Q
D
Y
E
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
F228
Y
Q
K
Y
G
N
D
F
T
E
D
Y
D
D
F
Honey Bee
Apis mellifera
XP_397589
236
27385
Y229
S
E
Y
G
D
Y
V
Y
D
D
Y
D
D
F
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
G234
F
D
D
F
G
Y
G
G
D
E
F
D
D
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
G222
F
I
P
G
R
G
G
G
Y
D
D
P
D
E
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
Y216
D
D
L
V
S
G
P
Y
D
A
M
D
D
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
93.3
80
53.3
86.6
N.A.
40
13.3
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
93.3
80
93.3
N.A.
60
20
N.A.
33.3
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
7
7
60
0
7
0
20
20
60
20
47
74
7
% D
% Glu:
0
7
0
0
7
7
7
0
0
14
14
7
54
7
0
% E
% Phe:
14
0
0
14
0
0
0
7
0
0
7
20
0
20
67
% F
% Gly:
7
67
60
14
20
74
67
14
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
20
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
7
54
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
7
7
47
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
14
54
0
14
7
74
7
0
14
47
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _