KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3J
All Species:
25.38
Human Site:
Y254
Identified Species:
39.88
UniProt:
O75822
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75822
NP_003749.2
258
29062
Y254
D
G
G
Y
V
Q
D
Y
E
D
F
M
_
_
_
Chimpanzee
Pan troglodytes
XP_523193
60
6489
Rhesus Macaque
Macaca mulatta
XP_001110624
258
29074
Y254
D
G
G
Y
V
Q
D
Y
E
D
F
M
_
_
_
Dog
Lupus familis
XP_544656
259
29118
Y255
D
G
G
Y
V
Q
D
Y
E
D
F
M
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q66JS6
263
29467
Y259
E
G
G
Y
V
Q
D
Y
E
D
F
M
_
_
_
Rat
Rattus norvegicus
A0JPM9
259
29169
Y255
D
G
G
Y
V
Q
D
Y
E
D
F
M
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513268
266
29964
F262
D
G
G
Y
V
Q
D
F
E
D
F
M
_
_
_
Chicken
Gallus gallus
Q5ZKA4
252
28706
F248
D
G
E
Y
V
Q
E
F
E
D
F
M
_
_
_
Frog
Xenopus laevis
Q6INR1
255
29320
F251
D
E
G
Y
G
R
E
F
D
D
F
M
_
_
_
Zebra Danio
Brachydanio rerio
Q7SXU0
249
28654
Y245
D
G
G
Y
A
Q
D
Y
E
D
F
M
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K550
236
26549
Y232
G
N
D
F
T
E
D
Y
D
D
F
M
_
_
_
Honey Bee
Apis mellifera
XP_397589
236
27385
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783857
241
26703
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150214
232
26006
P226
R
G
G
G
Y
D
D
P
D
E
Y
D
F
M
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850918
225
25150
D220
S
G
P
Y
D
A
M
D
D
D
D
F
M
_
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
99.6
97.6
N.A.
95
96.9
N.A.
72.9
81.7
66.6
66.2
N.A.
38.7
39.9
N.A.
43
Protein Similarity:
100
22.8
99.6
98
N.A.
95.8
97.3
N.A.
80.4
90.6
79.4
82.9
N.A.
57.7
59.2
N.A.
63.5
P-Site Identity:
100
0
100
100
N.A.
91.6
100
N.A.
91.6
75
50
91.6
N.A.
41.6
0
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
100
91.6
83.3
91.6
N.A.
66.6
0
N.A.
0
Percent
Protein Identity:
N.A.
33.7
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
53.4
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
21.4
N.A.
23
N.A.
N.A.
P-Site Similarity:
N.A.
42.8
N.A.
30.7
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
7
0
7
7
60
7
27
74
7
7
0
0
0
% D
% Glu:
7
7
7
0
0
7
14
0
54
7
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
20
0
0
67
7
7
0
0
% F
% Gly:
7
67
60
7
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
67
7
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
7
0
0
47
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
67
74
80
% _