KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINI2
All Species:
20
Human Site:
S329
Identified Species:
48.89
UniProt:
O75830
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75830
NP_006208.1
405
46145
S329
D
S
S
E
V
Y
V
S
Q
V
T
Q
K
V
F
Chimpanzee
Pan troglodytes
XP_516858
405
45980
S329
D
S
S
E
V
Y
V
S
Q
V
T
Q
K
V
F
Rhesus Macaque
Macaca mulatta
XP_001087507
329
37602
M256
E
V
Y
V
S
Q
V
M
Q
K
V
F
F
E
I
Dog
Lupus familis
XP_851407
422
47863
S346
D
S
A
E
V
F
V
S
Q
V
M
Q
H
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK88
405
45757
S329
D
S
S
E
V
Y
V
S
R
V
M
Q
K
V
F
Rat
Rattus norvegicus
Q9JLD2
410
46259
S334
D
K
K
E
L
F
L
S
K
A
V
H
K
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505567
473
53418
S397
D
D
K
D
V
F
L
S
K
A
I
H
K
S
F
Chicken
Gallus gallus
Q90935
410
46511
A334
D
N
K
E
L
Y
L
A
K
A
F
H
K
A
F
Frog
Xenopus laevis
Q52L45
377
42679
S304
N
S
G
S
A
D
L
S
G
M
S
G
S
N
N
Zebra Danio
Brachydanio rerio
NP_001122164
415
47025
G340
D
G
Q
D
L
F
I
G
K
A
V
Q
K
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
79.5
80.8
N.A.
75.8
37.7
N.A.
34.2
39
33.3
37.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
80.4
87.9
N.A.
85.6
63.4
N.A.
55.5
62.9
55
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
86.6
33.3
N.A.
33.3
33.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
93.3
60
N.A.
60
66.6
40
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
10
0
40
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
10
0
20
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
60
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
40
0
0
0
0
10
10
10
0
70
% F
% Gly:
0
10
10
0
0
0
0
10
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
30
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
10
% I
% Lys:
0
10
30
0
0
0
0
0
40
10
0
0
70
0
0
% K
% Leu:
0
0
0
0
30
0
40
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
10
20
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
0
40
0
0
50
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
50
30
10
10
0
0
70
0
0
10
0
10
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% T
% Val:
0
10
0
10
50
0
50
0
0
40
30
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
40
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _