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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD10
All Species:
26.67
Human Site:
Y199
Identified Species:
48.89
UniProt:
O75832
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75832
NP_002805.1
226
24428
Y199
V
S
Q
G
A
S
I
Y
I
E
N
K
E
E
K
Chimpanzee
Pan troglodytes
XP_001152908
119
13337
K104
I
Q
D
T
E
E
W
K
K
Q
N
C
W
C
L
Rhesus Macaque
Macaca mulatta
XP_001098141
226
24478
Y199
V
S
Q
G
A
S
I
Y
I
E
N
K
E
E
K
Dog
Lupus familis
XP_538135
226
24506
Y199
V
S
Q
G
A
S
I
Y
I
E
N
K
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2X2
231
25035
Y199
V
T
Q
G
A
S
I
Y
I
E
N
K
E
E
K
Rat
Rattus norvegicus
Q9Z2X3
231
24967
Y199
V
T
Q
G
A
S
I
Y
I
E
N
K
E
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420323
213
22312
H186
V
S
H
G
A
S
I
H
T
E
N
K
E
E
L
Frog
Xenopus laevis
Q4KL97
318
36054
N278
I
L
Y
G
V
N
L
N
I
K
N
C
A
G
K
Zebra Danio
Brachydanio rerio
NP_991317
226
24399
Y199
V
E
H
G
A
S
I
Y
I
E
N
K
E
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624339
224
24485
T195
V
Q
N
G
A
S
T
T
L
K
N
K
Q
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782225
221
23919
E195
V
E
H
G
A
S
L
E
I
V
N
K
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178442
240
25903
D209
I
R
H
G
A
D
V
D
V
E
D
K
E
G
Y
Baker's Yeast
Sacchar. cerevisiae
P50086
228
25598
Y201
V
E
K
Y
G
A
E
Y
D
L
V
D
N
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
99.5
98.6
N.A.
92.2
92.2
N.A.
N.A.
70.3
22.3
72.1
N.A.
N.A.
42.9
N.A.
50.4
Protein Similarity:
100
42.9
99.5
98.6
N.A.
95.6
96
N.A.
N.A.
79.1
37.4
84.9
N.A.
N.A.
61.9
N.A.
66.3
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
26.6
73.3
N.A.
N.A.
46.6
N.A.
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
80
53.3
80
N.A.
N.A.
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
32.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.1
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
77
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
8
0
% C
% Asp:
0
0
8
0
0
8
0
8
8
0
8
8
0
0
0
% D
% Glu:
0
24
0
0
8
8
8
8
0
62
0
0
70
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
85
8
0
0
0
0
0
0
0
0
16
8
% G
% His:
0
0
31
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
24
0
0
0
0
0
54
0
62
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
8
16
0
77
0
24
62
% K
% Leu:
0
8
0
0
0
0
16
0
8
8
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
0
8
0
0
85
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
39
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
31
0
0
0
70
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
16
0
8
0
0
8
8
8
0
0
0
0
0
0
% T
% Val:
77
0
0
0
8
0
8
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
8
8
0
0
0
54
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _