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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIB2 All Species: 15.15
Human Site: S57 Identified Species: 22.22
UniProt: O75838 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75838 NP_006374.1 187 21644 S57 P I V H V P M S L I I Q M P E
Chimpanzee Pan troglodytes XP_001148235 192 21656 C57 S L A P G P S C L S C T H S D
Rhesus Macaque Macaca mulatta XP_001112625 187 21884 E57 P D V K V P Y E L I G S M P E
Dog Lupus familis XP_548660 187 21696 S57 P I V H V P M S L I I Q M P E
Cat Felis silvestris
Mouse Mus musculus Q9Z309 187 21685 S57 P I V H V P M S L I I Q M P E
Rat Rattus norvegicus Q568Z7 187 21653 S57 P I V H V P M S L I I Q M P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510397 225 26316 E95 P E V K L P Y E L I R S M P E
Chicken Gallus gallus XP_413749 187 21661 Q57 P D V K L P M Q L I I N M P E
Frog Xenopus laevis Q3KQ77 208 24147 T60 F R N I L H N T F G M T D D M
Zebra Danio Brachydanio rerio NP_957000 187 21740 A57 P D V K V P L A L I V N M P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 R57 Q Q N P L V Q R V I D I F D A
Honey Bee Apis mellifera XP_623978 200 23103 I57 Q Q A S T L R I P L S C L T R
Nematode Worm Caenorhab. elegans NP_492514 311 35942 T179 R P A I T T L T F E E V E K M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81223 222 25675 F66 E E F Q L A L F R N R N R R N
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 A67 R I M E V F D A D N S G D V D
Red Bread Mold Neurospora crassa P87072 174 19751 E67 R M I A I F D E D G G G D V D
Conservation
Percent
Protein Identity: 100 80.7 62 97.8 N.A. 97.3 98.4 N.A. 51.5 78.6 23 75.9 N.A. 26.2 45.5 30.8 N.A.
Protein Similarity: 100 83.3 79.1 98.9 N.A. 99.4 99.4 N.A. 63.1 89.3 41.3 87.1 N.A. 45.9 66.5 43.7 N.A.
P-Site Identity: 100 13.3 60 100 N.A. 100 100 N.A. 53.3 66.6 0 60 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 26.6 60 100 N.A. 100 100 N.A. 60 73.3 20 80 N.A. 20 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.2 29.4 30.4
Protein Similarity: N.A. N.A. N.A. 37.8 48.6 49.7
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 7 0 7 0 13 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 7 7 0 0 0 % C
% Asp: 0 19 0 0 0 0 13 0 13 0 7 0 19 13 19 % D
% Glu: 7 13 0 7 0 0 0 19 0 7 7 0 7 0 50 % E
% Phe: 7 0 7 0 0 13 0 7 13 0 0 0 7 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 13 13 13 0 0 0 % G
% His: 0 0 0 25 0 7 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 32 7 13 7 0 0 7 0 57 32 7 0 0 0 % I
% Lys: 0 0 0 25 0 0 0 0 0 0 0 0 0 7 0 % K
% Leu: 0 7 0 0 32 7 19 0 57 7 0 0 7 0 0 % L
% Met: 0 7 7 0 0 0 32 0 0 0 7 0 50 0 13 % M
% Asn: 0 0 13 0 0 0 7 0 0 13 0 19 0 0 7 % N
% Pro: 50 7 0 13 0 57 0 0 7 0 0 0 0 50 0 % P
% Gln: 13 13 0 7 0 0 7 7 0 0 0 25 0 0 0 % Q
% Arg: 19 7 0 0 0 0 7 7 7 0 13 0 7 7 7 % R
% Ser: 7 0 0 7 0 0 7 25 0 7 13 13 0 7 0 % S
% Thr: 0 0 0 0 13 7 0 13 0 0 0 13 0 7 0 % T
% Val: 0 0 50 0 44 7 0 0 7 0 7 7 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _