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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPK1B All Species: 21.82
Human Site: T149 Identified Species: 53.33
UniProt: O75841 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75841 NP_008883.2 260 29671 T149 K N N G V T K T W D R L M L Q
Chimpanzee Pan troglodytes XP_526274 252 28692 D149 W D R L M L Q D N C C G V N G
Rhesus Macaque Macaca mulatta XP_001108219 260 29654 T149 K N N G V T K T W D R L M L Q
Dog Lupus familis XP_850140 349 39470 T238 K N N G V T K T W D R L M L Q
Cat Felis silvestris
Mouse Mus musculus Q9Z2C6 260 29743 T149 K N N G V T K T W D R L M L Q
Rat Rattus norvegicus Q566D0 260 29794 T149 K N S Y V T K T W D R L M L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508151 90 9596
Chicken Gallus gallus XP_416567 193 21972 T105 P L D W Q E Y T S A F R M T H
Frog Xenopus laevis NP_001086351 259 29279 T148 K I A G V T S T W N R F M L L
Zebra Danio Brachydanio rerio Q6GMK6 239 26765 E144 A W N I I Q A E W Q C C G V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 99.6 71.3 N.A. 91.1 89.6 N.A. 25 54.2 71.1 22.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 100 73.3 N.A. 96.9 96.5 N.A. 28.4 60.7 85.3 42.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 86.6 N.A. 0 13.3 60 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 93.3 N.A. 0 20 66.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 10 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 20 10 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 10 0 50 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 0 0 0 10 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 60 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 0 10 0 0 0 0 0 50 0 60 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 70 0 0 % M
% Asn: 0 50 50 0 0 0 0 0 10 10 0 0 0 10 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 10 10 0 0 10 0 0 0 0 50 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 60 10 0 0 0 % R
% Ser: 0 0 10 0 0 0 10 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 60 0 70 0 0 0 0 0 10 10 % T
% Val: 0 0 0 0 60 0 0 0 0 0 0 0 10 10 0 % V
% Trp: 10 10 0 10 0 0 0 0 70 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _