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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP1G2 All Species: 13.33
Human Site: S609 Identified Species: 24.44
UniProt: O75843 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75843 NP_003908.1 785 87117 S609 S K E A A Q L S E A A P V P T
Chimpanzee Pan troglodytes XP_001163717 785 87058 S609 S K E A A Q L S E A A P V P T
Rhesus Macaque Macaca mulatta XP_001109007 785 86931 S609 S K A A A Q L S E A V P A P T
Dog Lupus familis XP_537377 787 87286 S607 E S K E A Q L S E A S L V P T
Cat Felis silvestris
Mouse Mus musculus O88512 791 87846 E610 Q T E A Q P L E V T A P A P T
Rat Rattus norvegicus P18484 938 104026 G640 E R S I D V N G G P E P V P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509435 822 91369 L610 G E T E P A V L E T K P P P T
Chicken Gallus gallus NP_001006132 821 91444 P617 T A V L E T K P P H S G L Q P
Frog Xenopus laevis NP_001083997 812 90423 I610 G E T D P T I I D A K P V Q S
Zebra Danio Brachydanio rerio NP_955976 819 90933 N634 L L D L L G G N D V V P V I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 N644 P L T S A A Q N N A L V N N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792773 959 106235 P786 L D L S A P A P S S A P P P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12028 832 93606 S665 S D L L G E D S K A E S K A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97 90.3 N.A. 86.4 24 N.A. 60.4 59.9 59.3 60.3 N.A. 24 N.A. N.A. 42
Protein Similarity: 100 99.8 97.8 94.2 N.A. 91.7 44.5 N.A. 75.5 75.4 76.4 75.5 N.A. 44.2 N.A. N.A. 58.8
P-Site Identity: 100 100 80 60 N.A. 46.6 20 N.A. 26.6 0 20 13.3 N.A. 13.3 N.A. N.A. 26.6
P-Site Similarity: 100 100 80 73.3 N.A. 46.6 26.6 N.A. 40 20 46.6 33.3 N.A. 33.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 31 47 16 8 0 0 54 31 0 16 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 8 8 8 0 8 0 16 0 0 0 0 0 0 % D
% Glu: 16 16 24 16 8 8 0 8 39 0 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 0 8 8 8 8 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 8 0 0 0 0 0 8 0 % I
% Lys: 0 24 8 0 0 0 8 0 8 0 16 0 8 0 0 % K
% Leu: 16 16 16 24 8 0 39 8 0 0 8 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 16 8 0 0 0 8 8 0 % N
% Pro: 8 0 0 0 16 16 0 16 8 8 0 70 16 62 8 % P
% Gln: 8 0 0 0 8 31 8 0 0 0 0 0 0 16 8 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 31 8 8 16 0 0 0 39 8 8 16 8 0 0 24 % S
% Thr: 8 8 24 0 0 16 0 0 0 16 0 0 0 0 47 % T
% Val: 0 0 8 0 0 8 8 0 8 8 16 8 47 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _