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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
44.85
Human Site:
S258
Identified Species:
65.78
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S258
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S258
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S258
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Dog
Lupus familis
XP_539577
422
48642
D240
E
Y
S
V
L
N
K
D
I
L
E
E
S
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S258
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Rat
Rattus norvegicus
NP_001101444
475
54829
S258
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
S256
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Frog
Xenopus laevis
NP_001087923
465
53504
S253
K
V
Y
V
V
E
G
S
K
R
S
S
H
S
N
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
S253
K
L
Y
V
V
E
G
S
K
R
S
S
H
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
K250
L
F
V
V
E
G
S
K
R
S
S
H
S
N
A
Honey Bee
Apis mellifera
XP_623864
433
51054
S251
K
I
F
I
V
E
N
S
K
R
S
S
H
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
G229
H
S
N
A
Y
F
Y
G
F
F
K
N
K
R
I
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
G242
K
K
L
F
V
V
D
G
S
T
R
S
S
H
S
Maize
Zea mays
NP_001131195
425
48732
S243
K
L
F
V
V
D
G
S
T
R
S
S
H
S
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
G242
K
K
L
F
V
V
D
G
S
T
R
S
S
H
S
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
S256
K
I
F
V
I
D
G
S
K
R
S
S
H
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
13.3
73.3
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
26.6
93.3
N.A.
6.6
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
20
73.3
N.A.
20
73.3
N.A.
P-Site Similarity:
26.6
93.3
N.A.
26.6
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
13
7
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
7
57
0
0
0
0
7
7
0
0
0
% E
% Phe:
0
7
19
13
0
7
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
63
19
0
0
0
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
7
69
13
0
% H
% Ile:
0
13
0
7
7
0
0
0
7
0
0
0
0
0
7
% I
% Lys:
82
13
0
0
0
0
7
7
63
0
7
0
7
0
0
% K
% Leu:
7
13
13
0
7
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
0
0
7
7
0
0
0
0
7
0
7
69
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
69
13
0
0
7
0
% R
% Ser:
0
7
7
0
0
0
7
69
13
7
75
82
25
69
13
% S
% Thr:
0
0
0
0
0
0
0
0
7
13
0
0
0
0
0
% T
% Val:
0
44
7
75
75
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
50
0
7
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _