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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
30.91
Human Site:
S288
Identified Species:
45.33
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S288
D
T
L
L
E
E
Y
S
V
L
N
K
D
I
Q
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S288
D
T
L
L
E
E
Y
S
V
L
N
K
D
I
Q
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S288
D
T
L
L
E
E
Y
S
V
L
N
K
D
I
Q
Dog
Lupus familis
XP_539577
422
48642
G270
K
V
K
N
K
K
Q
G
C
K
N
E
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S288
D
T
L
L
E
E
Y
S
V
P
N
K
D
N
Q
Rat
Rattus norvegicus
NP_001101444
475
54829
S288
D
T
L
L
E
E
Y
S
V
P
N
K
D
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
S286
D
T
L
L
E
D
Y
S
A
L
N
K
E
P
V
Frog
Xenopus laevis
NP_001087923
465
53504
S283
D
T
L
L
E
D
Y
S
P
L
N
K
E
G
T
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
S283
D
T
L
L
E
D
Y
S
P
L
N
Q
S
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
K280
T
L
L
L
N
K
G
K
P
D
D
S
E
L
S
Honey Bee
Apis mellifera
XP_623864
433
51054
F281
D
T
L
V
K
E
Y
F
K
P
A
K
D
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
K259
E
E
G
E
K
K
K
K
T
G
C
N
T
E
E
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
C272
Y
D
T
L
I
Q
Q
C
K
D
D
E
E
I
V
Maize
Zea mays
NP_001131195
425
48732
S273
D
T
L
I
Q
Q
C
S
N
E
D
E
I
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
C272
Y
D
T
L
I
Q
Q
C
K
N
E
D
E
I
V
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
N286
F
D
T
L
V
N
S
N
S
T
D
E
I
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
66.6
60
N.A.
13.3
46.6
N.A.
0
P-Site Similarity:
100
100
100
40
N.A.
86.6
86.6
N.A.
N.A.
80
80
80
N.A.
40
60
N.A.
26.6
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
13.3
26.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
40
66.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
7
13
7
0
7
0
0
0
0
% C
% Asp:
63
19
0
0
0
19
0
0
0
13
25
7
38
0
0
% D
% Glu:
7
7
0
7
50
38
0
0
0
7
7
25
38
13
13
% E
% Phe:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
7
7
0
7
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
13
0
0
0
0
0
0
0
13
32
0
% I
% Lys:
7
0
7
0
19
19
7
13
19
7
0
50
0
0
0
% K
% Leu:
0
7
69
75
0
0
0
0
0
38
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
7
0
7
7
7
57
7
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
19
19
0
0
0
7
0
% P
% Gln:
0
0
0
0
7
19
19
0
0
0
0
7
0
0
32
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
57
7
0
0
7
7
0
13
% S
% Thr:
7
63
19
0
0
0
0
0
7
7
0
0
7
7
7
% T
% Val:
0
7
0
7
7
0
0
0
32
0
0
0
0
13
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
57
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _