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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
15.15
Human Site:
S298
Identified Species:
22.22
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S298
N
K
D
I
Q
E
D
S
G
M
E
P
R
N
E
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S298
N
K
D
I
Q
E
D
S
G
M
E
P
R
N
E
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S298
N
K
D
I
Q
E
D
S
G
M
E
P
R
N
E
Dog
Lupus familis
XP_539577
422
48642
L280
N
E
E
V
L
A
V
L
G
H
E
L
G
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S298
N
K
D
N
Q
E
E
S
G
M
E
A
R
N
E
Rat
Rattus norvegicus
NP_001101444
475
54829
P298
N
K
D
N
Q
E
E
P
G
L
E
P
R
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
E296
N
K
E
P
V
E
G
E
E
G
E
N
E
E
T
Frog
Xenopus laevis
NP_001087923
465
53504
T293
N
K
E
G
T
D
D
T
S
G
N
E
N
T
E
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
P293
N
Q
S
G
E
K
E
P
G
T
G
E
E
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
E290
D
S
E
L
S
E
E
E
K
G
K
G
C
T
D
Honey Bee
Apis mellifera
XP_623864
433
51054
K291
A
K
D
E
A
D
V
K
G
C
N
T
D
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
A269
C
N
T
E
E
V
L
A
V
L
A
H
E
L
G
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
I282
D
E
E
I
V
A
V
I
A
H
E
L
G
H
W
Maize
Zea mays
NP_001131195
425
48732
A283
D
E
I
V
S
V
I
A
H
E
L
G
H
W
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
I282
E
D
E
I
V
A
V
I
A
H
E
L
G
H
W
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
A296
D
E
I
T
A
V
L
A
H
E
I
G
H
W
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
20
N.A.
80
73.3
N.A.
N.A.
26.6
26.6
26.6
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
100
100
46.6
N.A.
86.6
86.6
N.A.
N.A.
33.3
46.6
53.3
N.A.
46.6
26.6
N.A.
20
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
13.3
0
N.A.
13.3
0
N.A.
P-Site Similarity:
40
33.3
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
13
19
0
19
13
0
7
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% C
% Asp:
25
7
38
0
0
13
25
0
0
0
0
0
7
0
7
% D
% Glu:
7
25
38
13
13
44
25
13
7
13
57
13
19
13
44
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
7
0
50
19
7
19
19
0
7
% G
% His:
0
0
0
0
0
0
0
0
13
19
0
7
13
19
0
% H
% Ile:
0
0
13
32
0
0
7
13
0
0
7
0
0
0
0
% I
% Lys:
0
50
0
0
0
7
0
7
7
0
7
0
0
0
7
% K
% Leu:
0
0
0
7
7
0
13
7
0
13
7
19
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% M
% Asn:
57
7
0
13
0
0
0
0
0
0
13
7
7
38
0
% N
% Pro:
0
0
0
7
0
0
0
13
0
0
0
25
0
0
0
% P
% Gln:
0
7
0
0
32
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
32
0
0
% R
% Ser:
0
7
7
0
13
0
0
25
7
0
0
0
0
0
0
% S
% Thr:
0
0
7
7
7
0
0
7
0
7
0
7
0
13
7
% T
% Val:
0
0
0
13
19
19
25
0
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
19
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _