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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
22.12
Human Site:
S310
Identified Species:
32.44
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S310
R
N
E
E
E
G
N
S
E
E
I
K
A
K
V
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S310
R
N
E
E
E
G
N
S
E
E
I
K
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S310
R
N
E
E
E
R
N
S
E
E
I
K
A
K
V
Dog
Lupus familis
XP_539577
422
48642
T292
G
H
W
K
L
G
H
T
V
K
N
I
I
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S310
R
N
E
G
E
G
D
S
E
E
V
K
A
K
V
Rat
Rattus norvegicus
NP_001101444
475
54829
S310
R
N
E
G
E
G
D
S
E
E
V
K
S
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
K308
E
E
T
K
S
K
T
K
N
K
K
Q
G
C
K
Frog
Xenopus laevis
NP_001087923
465
53504
V305
N
T
E
L
K
S
K
V
K
N
L
N
K
K
Q
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
E305
E
N
E
A
V
V
N
E
S
K
A
K
P
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
A302
C
T
D
E
E
V
L
A
V
L
G
H
E
L
G
Honey Bee
Apis mellifera
XP_623864
433
51054
A303
D
E
V
L
A
I
L
A
H
E
L
G
H
W
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
G281
E
L
G
H
W
K
L
G
H
N
L
K
N
L
I
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
T294
G
H
W
K
L
N
H
T
M
Y
S
F
I
A
V
Maize
Zea mays
NP_001131195
425
48732
V295
H
W
K
L
N
H
T
V
Y
S
F
V
A
V
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
T294
G
H
W
K
L
N
H
T
T
Y
S
F
I
A
V
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
V308
H
W
Q
K
N
H
I
V
N
M
V
I
F
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
93.3
6.6
N.A.
80
73.3
N.A.
N.A.
0
13.3
33.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
40
N.A.
93.3
93.3
N.A.
N.A.
20
33.3
40
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
33.3
13.3
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
13
0
0
7
0
32
13
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
7
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
19
13
44
25
38
0
0
7
32
38
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
13
7
0
0
% F
% Gly:
19
0
7
13
0
32
0
7
0
0
7
7
7
0
7
% G
% His:
13
19
0
7
0
13
19
0
13
0
0
7
7
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
0
19
13
19
7
7
% I
% Lys:
0
0
7
32
7
13
7
7
7
19
7
44
7
44
13
% K
% Leu:
0
7
0
19
19
0
19
0
0
7
19
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% M
% Asn:
7
38
0
0
13
13
25
0
13
13
7
7
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
19
% Q
% Arg:
32
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
7
0
32
7
7
13
0
7
7
7
% S
% Thr:
0
13
7
0
0
0
13
19
7
0
0
0
0
0
0
% T
% Val:
0
0
7
0
7
13
0
19
13
0
19
7
0
7
44
% V
% Trp:
0
13
19
0
7
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _