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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
31.52
Human Site:
S433
Identified Species:
46.22
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S433
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S433
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S433
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Dog
Lupus familis
XP_539577
422
48642
A381
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S433
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Rat
Rattus norvegicus
NP_001101444
475
54829
S433
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
S423
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Frog
Xenopus laevis
NP_001087923
465
53504
S423
G
K
A
K
D
L
Y
S
A
L
I
K
L
N
K
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
S426
G
R
S
S
E
L
Y
S
A
L
I
K
L
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
Q405
G
F
A
E
Q
L
G
Q
A
L
I
K
L
N
V
Honey Bee
Apis mellifera
XP_623864
433
51054
K392
L
G
H
G
E
A
L
K
S
S
L
I
K
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
R370
L
Q
R
A
S
Y
L
R
M
A
L
I
K
L
H
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
V383
S
A
L
R
G
G
L
V
K
L
Q
E
E
N
L
Maize
Zea mays
NP_001131195
425
48732
K384
Q
L
R
A
A
L
V
K
L
Q
E
E
N
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
V383
K
D
L
R
P
A
L
V
K
L
Q
E
E
N
L
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
R408
G
Y
K
Q
N
L
C
R
A
L
I
D
L
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
100
100
73.3
N.A.
60
0
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
66.6
26.6
N.A.
13.3
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
13.3
6.6
N.A.
13.3
40
N.A.
P-Site Similarity:
26.6
13.3
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
50
13
7
13
0
7
63
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
44
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
0
0
0
7
13
0
0
0
0
0
7
19
13
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
63
7
0
7
7
7
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
63
13
0
0
7
% I
% Lys:
13
44
13
44
0
0
0
13
13
0
7
57
13
7
50
% K
% Leu:
13
7
13
0
7
69
25
0
13
75
13
7
63
19
13
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
13
69
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
0
7
7
0
0
7
0
7
13
0
0
7
7
% Q
% Arg:
0
7
13
13
0
0
0
13
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
7
7
0
7
50
7
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
13
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
13
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _