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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
31.82
Human Site:
S81
Identified Species:
46.67
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
S81
K
S
T
F
S
F
W
S
G
L
Y
S
E
T
E
Chimpanzee
Pan troglodytes
XP_513352
475
54806
S81
K
S
T
F
S
F
W
S
G
L
Y
S
E
I
E
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
S81
K
S
T
F
S
F
W
S
G
L
Y
S
E
I
E
Dog
Lupus familis
XP_539577
422
48642
S65
D
S
E
T
F
E
K
S
R
L
Y
Q
L
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
S81
K
S
T
F
S
F
W
S
G
L
Y
S
E
V
E
Rat
Rattus norvegicus
NP_001101444
475
54829
S81
K
S
T
F
S
F
W
S
G
L
Y
S
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
S79
K
S
T
F
S
F
W
S
G
L
Y
S
E
L
E
Frog
Xenopus laevis
NP_001087923
465
53504
S76
K
S
T
F
S
F
W
S
G
L
Y
S
E
A
E
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
S76
K
S
N
F
G
F
W
S
G
L
Y
S
E
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
M75
G
I
F
K
A
V
V
M
D
V
A
L
L
C
M
Honey Bee
Apis mellifera
XP_623864
433
51054
I76
K
F
D
S
F
E
S
I
Y
S
E
L
C
T
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
L54
E
S
S
I
I
L
V
L
G
G
I
P
Y
L
W
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
E67
S
H
F
N
F
V
H
E
F
V
T
I
L
L
D
Maize
Zea mays
NP_001131195
425
48732
A68
Y
F
H
F
V
H
E
A
V
T
I
L
M
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
E67
S
Y
F
H
F
V
H
E
F
V
T
I
L
M
D
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
Y79
F
S
I
F
G
D
V
Y
N
L
A
Q
K
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
93.3
93.3
26.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
80
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
33.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
80
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
0
6.6
N.A.
0
20
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
0
13
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% C
% Asp:
7
0
7
0
0
7
0
0
7
0
0
0
0
13
13
% D
% Glu:
7
0
7
0
0
13
7
13
0
0
7
0
50
0
50
% E
% Phe:
7
13
19
63
25
50
0
0
13
0
0
0
0
7
0
% F
% Gly:
7
0
0
0
13
0
0
0
57
7
0
0
0
0
0
% G
% His:
0
7
7
7
0
7
13
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
7
0
0
7
0
0
13
13
0
13
0
% I
% Lys:
57
0
0
7
0
0
7
0
0
0
0
0
7
0
7
% K
% Leu:
0
0
0
0
0
7
0
7
0
63
0
19
25
25
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
7
13
% M
% Asn:
0
0
7
7
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
13
69
7
7
44
0
7
57
0
7
0
50
0
0
0
% S
% Thr:
0
0
44
7
0
0
0
0
0
7
13
0
0
13
7
% T
% Val:
0
0
0
0
7
19
19
0
7
19
0
0
0
13
7
% V
% Trp:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
7
% W
% Tyr:
7
7
0
0
0
0
0
7
7
0
57
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _