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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
29.7
Human Site:
Y118
Identified Species:
43.56
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
Y118
Y
A
G
F
G
P
E
Y
E
I
T
Q
S
L
V
Chimpanzee
Pan troglodytes
XP_513352
475
54806
Y118
Y
A
G
F
G
P
E
Y
E
I
T
Q
S
L
V
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
Y118
Y
A
G
F
G
P
E
Y
E
I
T
Q
S
L
V
Dog
Lupus familis
XP_539577
422
48642
L102
G
I
P
Y
L
W
R
L
S
G
R
F
C
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
Y118
S
A
G
F
G
P
E
Y
E
I
I
Q
S
L
V
Rat
Rattus norvegicus
NP_001101444
475
54829
Y118
S
A
G
F
G
P
E
Y
E
I
I
Q
S
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
Y116
R
A
G
F
G
P
E
Y
E
I
V
Q
S
L
V
Frog
Xenopus laevis
NP_001087923
465
53504
Y113
R
A
G
F
S
A
E
Y
E
I
I
H
S
L
V
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
Y113
H
F
G
F
G
P
E
Y
E
I
S
Q
S
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
I112
W
D
S
K
N
E
I
I
V
S
C
V
F
V
L
Honey Bee
Apis mellifera
XP_623864
433
51054
I113
G
F
N
D
E
N
E
I
L
L
S
G
I
C
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
V91
A
F
M
L
L
A
S
V
F
S
T
F
V
G
L
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
E104
A
G
F
N
E
E
N
E
I
L
H
T
L
A
F
Maize
Zea mays
NP_001131195
425
48732
I105
G
L
S
A
E
N
E
I
I
H
T
L
A
F
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
E104
L
G
L
D
P
E
N
E
I
L
H
T
L
S
F
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
S116
P
V
R
F
H
M
V
S
T
V
A
Q
S
L
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
N.A.
86.6
66.6
80
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
66.6
93.3
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
0
13.3
N.A.
0
26.6
N.A.
P-Site Similarity:
6.6
26.6
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
44
0
7
0
13
0
0
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
7
7
7
% C
% Asp:
0
7
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
19
19
63
13
50
0
0
0
0
0
0
% E
% Phe:
0
19
7
57
0
0
0
0
7
0
0
13
7
7
13
% F
% Gly:
19
13
50
0
44
0
0
0
0
7
0
7
0
13
0
% G
% His:
7
0
0
0
7
0
0
0
0
7
13
7
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
19
19
50
19
0
7
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
7
7
13
0
0
7
7
19
0
7
13
57
19
% L
% Met:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
7
7
13
13
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
7
0
7
44
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% Q
% Arg:
13
0
7
0
0
0
7
0
0
0
7
0
0
0
0
% R
% Ser:
13
0
13
0
7
0
7
7
7
13
13
0
57
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
32
13
0
0
0
% T
% Val:
0
7
0
0
0
0
7
7
7
7
7
7
7
7
50
% V
% Trp:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
7
0
0
0
50
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _