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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMPSTE24
All Species:
31.21
Human Site:
Y45
Identified Species:
45.78
UniProt:
O75844
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75844
NP_005848.2
475
54813
Y45
A
Q
R
Q
R
R
I
Y
K
T
T
T
H
V
P
Chimpanzee
Pan troglodytes
XP_513352
475
54806
Y45
A
Q
R
Q
R
R
I
Y
K
T
T
T
H
V
P
Rhesus Macaque
Macaca mulatta
XP_001082852
475
54874
Y45
A
Q
R
Q
R
R
I
Y
K
T
T
T
H
V
P
Dog
Lupus familis
XP_539577
422
48642
Y29
L
L
F
S
W
T
V
Y
L
W
E
T
F
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80W54
475
54716
Y45
A
Q
R
Q
R
R
I
Y
K
T
T
T
R
V
P
Rat
Rattus norvegicus
NP_001101444
475
54829
Y45
A
Q
R
Q
R
R
I
Y
K
T
T
T
H
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417720
465
53514
Y43
A
H
R
Q
R
R
V
Y
R
T
T
T
H
V
P
Frog
Xenopus laevis
NP_001087923
465
53504
Y40
S
N
R
Q
R
K
I
Y
R
T
T
T
H
V
P
Zebra Danio
Brachydanio rerio
NP_956186
468
53723
Y40
A
Y
R
Q
R
K
I
Y
R
A
T
V
H
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611175
451
51621
L39
V
K
V
Y
Q
T
A
L
K
V
P
A
E
L
K
Honey Bee
Apis mellifera
XP_623864
433
51054
R40
R
Q
R
V
F
M
M
R
L
T
N
L
P
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177479
411
47353
I18
P
S
S
L
K
D
V
I
D
N
E
T
F
E
K
Poplar Tree
Populus trichocarpa
XP_002320821
424
48433
L31
D
L
R
Q
R
A
A
L
K
L
P
I
L
P
K
Maize
Zea mays
NP_001131195
425
48732
K32
I
R
Q
H
R
A
L
K
L
P
T
L
P
K
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX88
424
48464
L31
D
L
R
Q
L
T
A
L
K
L
P
T
L
P
K
Baker's Yeast
Sacchar. cerevisiae
P47154
453
52306
E43
R
Q
Y
Q
K
L
S
E
T
K
L
P
P
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
85.4
N.A.
93.4
93.6
N.A.
N.A.
86.9
80.4
79.1
N.A.
48
41.8
N.A.
63.3
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96
96.4
N.A.
N.A.
92.2
87.3
87.7
N.A.
67.3
61
N.A.
72.8
P-Site Identity:
100
100
100
13.3
N.A.
93.3
100
N.A.
N.A.
80
73.3
66.6
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
100
N.A.
N.A.
93.3
93.3
80
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
43.3
44.6
N.A.
43.5
34.7
N.A.
Protein Similarity:
59.7
61
N.A.
60.6
52.6
N.A.
P-Site Identity:
26.6
20
N.A.
26.6
20
N.A.
P-Site Similarity:
26.6
40
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
0
0
0
0
13
19
0
0
7
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
13
0
7
7
0
% E
% Phe:
0
0
7
0
7
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
44
0
0
% H
% Ile:
7
0
0
0
0
0
44
7
0
0
0
7
0
0
0
% I
% Lys:
0
7
0
0
13
13
0
7
50
7
0
0
0
13
25
% K
% Leu:
7
19
0
7
7
7
7
19
19
13
7
13
13
13
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
7
7
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
7
19
7
19
13
57
% P
% Gln:
0
44
7
69
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
7
69
0
63
38
0
7
19
0
0
0
7
0
0
% R
% Ser:
7
7
7
7
0
0
7
0
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
19
0
0
7
50
57
63
0
0
0
% T
% Val:
7
0
7
7
0
0
19
0
0
7
0
7
0
57
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
7
7
7
0
0
0
57
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _