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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SC5DL
All Species:
17.27
Human Site:
S279
Identified Species:
29.23
UniProt:
O75845
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75845
NP_001020127.1
299
35301
S279
M
T
E
G
K
R
S
S
H
S
G
N
G
C
K
Chimpanzee
Pan troglodytes
XP_508825
299
35216
S279
M
T
E
G
K
R
S
S
H
S
G
N
G
C
K
Rhesus Macaque
Macaca mulatta
XP_001107388
299
35193
S279
M
T
E
G
K
Y
S
S
H
A
G
N
G
C
K
Dog
Lupus familis
XP_853004
299
35489
T279
M
T
E
E
K
C
N
T
H
T
K
N
G
C
K
Cat
Felis silvestris
Mouse
Mus musculus
O88822
299
35044
S279
M
T
E
K
E
S
N
S
F
A
E
N
G
C
K
Rat
Rattus norvegicus
O35532
293
34945
W268
Y
A
S
T
F
T
W
W
D
R
I
F
G
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505296
299
35239
E279
M
T
E
E
K
M
S
E
H
A
G
N
G
C
K
Chicken
Gallus gallus
Q5ZLL6
296
35467
W268
Y
A
S
T
F
T
W
W
D
R
I
F
G
T
D
Frog
Xenopus laevis
NP_001087137
287
34181
L268
E
G
N
G
P
H
A
L
C
K
K
L
E
E
E
Zebra Danio
Brachydanio rerio
Q7ZW77
291
34789
W268
Y
G
S
T
F
T
W
W
D
R
L
F
D
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793331
305
35863
S280
L
A
N
T
G
P
L
S
C
Q
S
K
A
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39208
281
33124
S262
W
M
D
W
M
F
G
S
L
R
D
P
L
L
E
Baker's Yeast
Sacchar. cerevisiae
P32353
365
42712
E338
T
W
D
A
Q
V
K
E
V
E
H
F
I
K
E
Red Bread Mold
Neurospora crassa
Q7SBB6
344
40644
E319
T
W
K
K
Q
V
N
E
M
E
K
I
V
K
E
Conservation
Percent
Protein Identity:
100
98.3
95.9
87.2
N.A.
83.2
27
N.A.
74.5
25.7
68.5
21.7
N.A.
N.A.
N.A.
N.A.
57.3
Protein Similarity:
100
99.6
97.6
94.3
N.A.
92.3
43.1
N.A.
88.9
43.1
81.6
41.8
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
100
86.6
60
N.A.
53.3
6.6
N.A.
73.3
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
73.3
6.6
N.A.
80
6.6
20
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
39.1
42.1
Protein Similarity:
N.A.
N.A.
N.A.
50.1
56.9
59
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
8
0
0
8
0
0
22
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
15
0
0
0
0
43
0
% C
% Asp:
0
0
15
0
0
0
0
0
22
0
8
0
8
0
22
% D
% Glu:
8
0
43
15
8
0
0
22
0
15
8
0
8
8
29
% E
% Phe:
0
0
0
0
22
8
0
0
8
0
0
29
0
0
0
% F
% Gly:
0
15
0
29
8
0
8
0
0
0
29
0
58
0
0
% G
% His:
0
0
0
0
0
8
0
0
36
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
8
8
0
0
% I
% Lys:
0
0
8
15
36
0
8
0
0
8
22
8
0
22
43
% K
% Leu:
8
0
0
0
0
0
8
8
8
0
8
8
8
8
0
% L
% Met:
43
8
0
0
8
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
22
0
0
0
0
43
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
29
0
0
0
0
0
% R
% Ser:
0
0
22
0
0
8
29
43
0
15
8
0
0
0
8
% S
% Thr:
15
43
0
29
0
22
0
8
0
8
0
0
0
22
0
% T
% Val:
0
0
0
0
0
15
0
0
8
0
0
0
8
0
0
% V
% Trp:
8
15
0
8
0
0
22
22
0
0
0
0
0
0
0
% W
% Tyr:
22
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _