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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7B1
All Species:
13.33
Human Site:
S115
Identified Species:
29.33
UniProt:
O75881
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75881
NP_004811.1
506
58256
S115
Q
L
S
F
R
V
F
S
N
K
L
L
E
K
A
Chimpanzee
Pan troglodytes
XP_001159731
506
58281
S115
Q
L
S
F
R
V
F
S
N
K
L
L
E
K
A
Rhesus Macaque
Macaca mulatta
XP_001098766
558
64044
S168
Q
L
S
F
R
L
F
S
N
K
L
L
E
K
A
Dog
Lupus familis
XP_544102
558
64067
N168
L
S
F
R
I
F
S
N
K
L
S
R
K
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60991
507
58399
S113
Q
L
S
F
Q
K
F
S
S
R
L
S
A
K
A
Rat
Rattus norvegicus
Q63688
414
48208
D56
L
L
Q
G
K
S
L
D
G
L
L
E
T
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512397
571
66419
A108
H
F
D
F
K
G
F
A
N
H
L
G
Q
K
I
Chicken
Gallus gallus
XP_418276
818
92343
A421
Q
L
E
F
H
E
F
A
D
K
M
A
S
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699028
504
58566
A103
F
H
T
F
S
D
S
A
A
S
R
T
F
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMT6
501
58204
N105
T
D
F
R
S
F
H
N
N
E
W
R
N
F
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
T110
K
Y
V
A
Y
N
H
T
T
V
G
T
A
P
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
64.3
N.A.
64.8
52.7
N.A.
43.4
34.3
N.A.
42.4
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
86.9
75.8
N.A.
79.4
67.5
N.A.
59.7
46
N.A.
61.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
60
13.3
N.A.
33.3
40
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
80
20
N.A.
53.3
60
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
28
10
0
0
10
19
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
10
0
10
10
0
0
0
0
10
0
% D
% Glu:
0
0
10
0
0
10
0
0
0
10
0
10
28
0
0
% E
% Phe:
10
10
19
64
0
19
55
0
0
0
0
0
10
10
10
% F
% Gly:
0
0
0
10
0
10
0
0
10
0
10
10
0
0
0
% G
% His:
10
10
0
0
10
0
19
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
10
0
0
0
19
10
0
0
10
37
0
0
10
55
0
% K
% Leu:
19
55
0
0
0
10
10
0
0
19
55
28
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
19
46
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
46
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
19
28
0
0
0
0
10
10
19
0
0
0
% R
% Ser:
0
10
37
0
19
10
19
37
10
10
10
10
10
0
0
% S
% Thr:
10
0
10
0
0
0
0
10
10
0
0
19
10
0
10
% T
% Val:
0
0
10
0
0
19
0
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _